Successful management of rocuronium-induced anaphylactic reactions with sugammadex: A case report

Takashi Kawano, Takahiko Tamura, Mayuko Hamaguchi, Tomoaki Yatabe, Koichi Yamashita, Masataka Yokoyama

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

Sugammadex, a new reversal agent for rocuronium, encapsulates the rocuronium molecule and results in rapid reversal of rocuronium-induced neuromuscular blockade. A case in which sugammadex was used to treat an anaphylactic reaction that occurred after rocuronium is presented. The binding/encapsulation of rocuronium by sugammadex may selectively eliminate the antigenic quaternary ammonium activity of circulating rocuronium, and prevent the propagation of rocuronium-induced anaphylaxis.

Original languageEnglish
Pages (from-to)62-64
Number of pages3
JournalJournal of Clinical Anesthesia
Volume24
Issue number1
DOIs
Publication statusPublished - 02-2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

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