Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion

M. Yazaki; M. Andoh; T. Ito; T. Ohno; Y. Wada

doi:10.1038/sj.bmt.1700663

Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion

M. Yazaki, M. Andoh, T. Ito, T. Ohno, Y. Wada

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Donor leukocyte infusion (DLI) was carried out on a 12-year-old girl with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph⁺ ALL) who received allogeneic bone marrow transplantation from an HLA-identical sibling. This is the first report of DLI use before the onset of hematological relapse monitored by the results of RT-PCR. This patient has been in CR for 11 months after BMT, suggesting this alternative treatment is promising for Ph⁺ ALL with positive reverse transcriptase-polymerase chain reaction (RT-PCR) following BMT.

Original language	English
Pages (from-to)	393-394
Number of pages	2
Journal	Bone Marrow Transplantation
Volume	19
Issue number	4
DOIs	https://doi.org/10.1038/sj.bmt.1700663
Publication status	Published - 02-02-1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Hematology
Transplantation

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10.1038/sj.bmt.1700663

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abstract = "Donor leukocyte infusion (DLI) was carried out on a 12-year-old girl with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who received allogeneic bone marrow transplantation from an HLA-identical sibling. This is the first report of DLI use before the onset of hematological relapse monitored by the results of RT-PCR. This patient has been in CR for 11 months after BMT, suggesting this alternative treatment is promising for Ph+ ALL with positive reverse transcriptase-polymerase chain reaction (RT-PCR) following BMT.",

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Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion. / Yazaki, M.; Andoh, M.; Ito, T. et al.

In: Bone Marrow Transplantation, Vol. 19, No. 4, 02.02.1997, p. 393-394.

Research output: Contribution to journal › Article › peer-review

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AU - Wada, Y.

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Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion

Abstract

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