Successful prevention of hematological relapse for a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation by donor leukocyte infusion

M. Yazaki, M. Andoh, T. Ito, T. Ohno, Y. Wada

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Donor leukocyte infusion (DLI) was carried out on a 12-year-old girl with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who received allogeneic bone marrow transplantation from an HLA-identical sibling. This is the first report of DLI use before the onset of hematological relapse monitored by the results of RT-PCR. This patient has been in CR for 11 months after BMT, suggesting this alternative treatment is promising for Ph+ ALL with positive reverse transcriptase-polymerase chain reaction (RT-PCR) following BMT.

Original languageEnglish
Pages (from-to)393-394
Number of pages2
JournalBone Marrow Transplantation
Volume19
Issue number4
DOIs
Publication statusPublished - 02-02-1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hematology
  • Transplantation

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