Successful treatment of iga vasculitis complicated with bowel perforation and crescentic glomerulonephritis by combination therapy of glucocorticoid, cyclosporine and factor XIII replacement

Keiko Koshiba, Sei Muraoka, Toshihiro Nanki, Satoru Komatsumoto

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

We report the findings of an 18-year-old boy with immunoglobulin A vasculitis (IgAV) complicated with bowel perforation and nephritis. He presented with abdominal pain, arthralgia and palpable purpura. Massive proteinuria developed during his clinical course. The patient was treated successfully using combination therapy of glucocorticoid (GC), cyclosporine (CYA) and factor XIII (F XIII) replacement. A standard treatment strategy for severe IgAV patients has not been established due to its rarity. Combination therapy using GC, CYA and F XIII replacement should be considered for severe IgAV patients.

Original languageEnglish
Pages (from-to)3035-3040
Number of pages6
JournalInternal Medicine
Volume57
Issue number20
DOIs
Publication statusPublished - 2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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