Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

Norihito Omote; Yoshihiro Kanemitsu; Takahiro Inoue; Toshiyuki Yonezawa; Takuji Ichihashi; Yuichiro Shindo; Koji Sakamoto; Akira Ando; Atsushi Suzuki; Akio Niimi; Satoru Ito; Kazuyoshi Imaizumi; Naozumi Hashimoto

doi:10.2169/internalmedicine.8163-21

Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

Norihito Omote, Yoshihiro Kanemitsu, Takahiro Inoue, Toshiyuki Yonezawa, Takuji Ichihashi, Yuichiro Shindo, Koji Sakamoto, Akira Ando, Atsushi Suzuki, Akio Niimi, Satoru Ito, Kazuyoshi Imaizumi, Naozumi Hashimoto

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

Original language	English
Pages (from-to)	233-236
Number of pages	4
Journal	Internal Medicine
Volume	61
Issue number	2
DOIs	https://doi.org/10.2169/internalmedicine.8163-21
Publication status	Published - 2022

All Science Journal Classification (ASJC) codes

Internal Medicine

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Omote, N., Kanemitsu, Y., Inoue, T., Yonezawa, T., Ichihashi, T., Shindo, Y., Sakamoto, K., Ando, A., Suzuki, A., Niimi, A., Ito, S., Imaizumi, K., & Hashimoto, N. (2022). Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19. Internal Medicine, 61(2), 233-236. https://doi.org/10.2169/internalmedicine.8163-21

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title = "Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19",

abstract = "We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.",

author = "Norihito Omote and Yoshihiro Kanemitsu and Takahiro Inoue and Toshiyuki Yonezawa and Takuji Ichihashi and Yuichiro Shindo and Koji Sakamoto and Akira Ando and Atsushi Suzuki and Akio Niimi and Satoru Ito and Kazuyoshi Imaizumi and Naozumi Hashimoto",

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Omote, N, Kanemitsu, Y, Inoue, T, Yonezawa, T, Ichihashi, T, Shindo, Y, Sakamoto, K, Ando, A, Suzuki, A, Niimi, A, Ito, S, Imaizumi, K & Hashimoto, N 2022, 'Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19', Internal Medicine, vol. 61, no. 2, pp. 233-236. https://doi.org/10.2169/internalmedicine.8163-21

TY - JOUR

T1 - Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

AU - Omote, Norihito

AU - Kanemitsu, Yoshihiro

AU - Inoue, Takahiro

AU - Yonezawa, Toshiyuki

AU - Ichihashi, Takuji

AU - Shindo, Yuichiro

AU - Sakamoto, Koji

AU - Ando, Akira

AU - Suzuki, Atsushi

AU - Niimi, Akio

AU - Ito, Satoru

AU - Imaizumi, Kazuyoshi

AU - Hashimoto, Naozumi

PY - 2022

Y1 - 2022

N2 - We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

AB - We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

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Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

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