Successfully resected advanced gastric carcinoma after combined chemotherapy of TS-1 plus CDDP--a case report

Akira Yasuda, Isamu Mizuno, Noriaki Mohri, Kozo Matsumoto, Shunsuke Fukaya, Nagao Shinagawa, Tadao Manabe

Research output: Contribution to journalArticle

Abstract

A 66-year-old man complained of epigastralgia and a close examination was done. A type 3 gastric carcinoma was found. The tumor invading the pancreas and swelling lymphnodes around the stomach were confirmed according to abdominal CT. We considered it difficult to resect the tumor completely, and so we used combined chemotherapy of TS-1 plus CDDP. TS-1 was taken at 120 mg/day for 28 days followed by 14 days rest. CDDP was injected at 140 mg on day 8. Because the tumor in the stomach changed to scar and swelling lymphnodes diminished after two courses of therapy, total gastrectomy was done. After operation, combined chemotherapy of LV and 5-FU resulted in no recurrence to date. Although combined chemotherapy of TS-1 plus CDDP is effective for advanced gastric carcinoma, the number of days TS-1 is taken and the duration of the preoperative chemotherapy must be investigated in forthcoming study.

Original languageEnglish
Pages (from-to)837-839
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume32
Issue number6
Publication statusPublished - 06-2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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    Yasuda, A., Mizuno, I., Mohri, N., Matsumoto, K., Fukaya, S., Shinagawa, N., & Manabe, T. (2005). Successfully resected advanced gastric carcinoma after combined chemotherapy of TS-1 plus CDDP--a case report. Gan to kagaku ryoho. Cancer & chemotherapy, 32(6), 837-839.