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Sunitinib Versus Sorafenib as Initial Targeted Therapy for mCC-RCC With Favorable/Intermediate Risk: Multicenter Randomized Trial CROSS-J-RCC

  • Yoshihiko Tomita
  • , Sei Naito
  • , Naoto Sassa
  • , Atsushi Takahashi
  • , Tsunenori Kondo
  • , Takuya Koie
  • , Wataru Obara
  • , Yasuyuki Kobayashi
  • , Jun Teishima
  • , Masayuki Takahashi
  • , Hideyasu Matsuyama
  • , Takeshi Ueda
  • , Kenya Yamaguchi
  • , Takeshi Kishida
  • , Ryoichi Shiroki
  • , Takashi Saika
  • , Nobuo Shinohara
  • , Mototsugu Oya
  • , Hiro omi Kanayama

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the present randomized controlled study was to compare the efficacy of sunitinib and sorafenib as first-line treatment of patients with metastatic clear cell renal cell carcinoma with favorable or intermediate Memorial Sloan Kettering Cancer Center risk. The median first progression-free survival was 8.7 and 7.0 months in the sunitinib and sorafenib groups, respectively (hazard ratio, 0.67; 95% confidence interval, 0.42-1.08).

Original languageEnglish
Pages (from-to)e374-e385
JournalClinical Genitourinary Cancer
Volume18
Issue number4
DOIs
Publication statusPublished - 08-2020
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Oncology
  • Urology

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