Superiority illusion arises from resting-state brain networks modulated by dopamine

Makiko Yamada; Lucina Q. Uddin; Hidehiko Takahashi; Yasuyuki Kimura; Keisuke Takahata; Ririko Kousa; Yoko Ikoma; Yoko Eguchi; Harumasa Takano; Hiroshi Ito; Makoto Higuchi; Tetsuya Suhara

doi:10.1073/pnas.1221681110

Superiority illusion arises from resting-state brain networks modulated by dopamine

Makiko Yamada, Lucina Q. Uddin, Hidehiko Takahashi, Yasuyuki Kimura, Keisuke Takahata, Ririko Kousa, Yoko Ikoma, Yoko Eguchi, Harumasa Takano, Hiroshi Ito, Makoto Higuchi, Tetsuya Suhara

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The majority of individuals evaluate themselves as superior to average. This is a cognitive biasknownas the "superiority illusion." This illusion helps us to have hope for the future and is deep-rooted in the process of human evolution. In this study, we examined the default states of neural andmolecular systems that generate this illusion, using resting-state functional MRI and PET. Resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. Our findings help elucidate how this key aspect of the human mind is biologically determined, and identify potential molecular and neural targets for treatment for depressive realism.

Original language	English
Pages (from-to)	4363-4367
Number of pages	5
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	110
Issue number	11
DOIs	https://doi.org/10.1073/pnas.1221681110
Publication status	Published - 12-03-2013
Externally published	Yes

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Yamada, M., Uddin, L. Q., Takahashi, H., Kimura, Y., Takahata, K., Kousa, R., Ikoma, Y., Eguchi, Y., Takano, H., Ito, H., Higuchi, M., & Suhara, T. (2013). Superiority illusion arises from resting-state brain networks modulated by dopamine. Proceedings of the National Academy of Sciences of the United States of America, 110(11), 4363-4367. https://doi.org/10.1073/pnas.1221681110

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abstract = "The majority of individuals evaluate themselves as superior to average. This is a cognitive biasknownas the {"}superiority illusion.{"} This illusion helps us to have hope for the future and is deep-rooted in the process of human evolution. In this study, we examined the default states of neural andmolecular systems that generate this illusion, using resting-state functional MRI and PET. Resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. Our findings help elucidate how this key aspect of the human mind is biologically determined, and identify potential molecular and neural targets for treatment for depressive realism.",

author = "Makiko Yamada and Uddin, {Lucina Q.} and Hidehiko Takahashi and Yasuyuki Kimura and Keisuke Takahata and Ririko Kousa and Yoko Ikoma and Yoko Eguchi and Harumasa Takano and Hiroshi Ito and Makoto Higuchi and Tetsuya Suhara",

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Yamada, M, Uddin, LQ, Takahashi, H, Kimura, Y, Takahata, K, Kousa, R, Ikoma, Y, Eguchi, Y, Takano, H, Ito, H, Higuchi, M & Suhara, T 2013, 'Superiority illusion arises from resting-state brain networks modulated by dopamine', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 11, pp. 4363-4367. https://doi.org/10.1073/pnas.1221681110

TY - JOUR

T1 - Superiority illusion arises from resting-state brain networks modulated by dopamine

AU - Yamada, Makiko

AU - Uddin, Lucina Q.

AU - Takahashi, Hidehiko

AU - Kimura, Yasuyuki

AU - Takahata, Keisuke

AU - Kousa, Ririko

AU - Ikoma, Yoko

AU - Eguchi, Yoko

AU - Takano, Harumasa

AU - Ito, Hiroshi

AU - Higuchi, Makoto

AU - Suhara, Tetsuya

PY - 2013/3/12

Y1 - 2013/3/12

N2 - The majority of individuals evaluate themselves as superior to average. This is a cognitive biasknownas the "superiority illusion." This illusion helps us to have hope for the future and is deep-rooted in the process of human evolution. In this study, we examined the default states of neural andmolecular systems that generate this illusion, using resting-state functional MRI and PET. Resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. Our findings help elucidate how this key aspect of the human mind is biologically determined, and identify potential molecular and neural targets for treatment for depressive realism.

AB - The majority of individuals evaluate themselves as superior to average. This is a cognitive biasknownas the "superiority illusion." This illusion helps us to have hope for the future and is deep-rooted in the process of human evolution. In this study, we examined the default states of neural andmolecular systems that generate this illusion, using resting-state functional MRI and PET. Resting-state functional connectivity between the frontal cortex and striatum regulated by inhibitory dopaminergic neurotransmission determines individual levels of the superiority illusion. Our findings help elucidate how this key aspect of the human mind is biologically determined, and identify potential molecular and neural targets for treatment for depressive realism.

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Superiority illusion arises from resting-state brain networks modulated by dopamine

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