Surgical treatment for adrenal metastasis from lung cancer

S. Itou, T. Imai, N. Usami, M. Uchiyama, A. Yasuda, K. Kawaguchi, K. Yokoi

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Several long-term survivors after surgical resection for a solitary adrenal metastasis from non-small cell lung cancer (NSCLC) have been reported in case reports and case series with a small number of patients. We have experienced 6 cases of patients who had adrenalectomy (ADR) for a metastasis from NSCLC. The median survival time (MST) after ADR was 24 months, and there was only 1 case of 3-year survivor. To elucidate the surgical indication and the prognostic factors of patients with a solitary adrenal metastasis from NSCLC, we analyzed 104 patients including our 6 patients who had ADR for a metastasis from NSCLC. The MST after ADR and 5-year survival were 24 months and 31%, respectively. Univariate and multivariate analysis demonstrated that lymph node metastasis at the surgery for primary lung cancer was the only significant and independent predictor of poor survival in patients after ADR. The results suggest that aggressive surgical treatment of a solitary adrenal metastasis from NSCLC may be effective when a patient have N0 disease.

Original languageEnglish
Pages (from-to)47-52
Number of pages6
JournalKyobu geka. The Japanese journal of thoracic surgery
Volume59
Issue number1
Publication statusPublished - 01-2006
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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