Abstract
The increase in multidrug-resistant Gram-negative bacterial infections has forced the reintroduction of antibiotics such as colistin. However, the spread of the plasmid-borne mcr-1 colistin resistance gene have moved us closer to an era of untreatable Gram-negative infections. To evaluate whether predatory bacteria could be used as a potential therapeutic to treat this upcoming threat, the ability of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus to prey on several clinically relevant mcr-1-positive, colistin-resistant isolates was evaluated. No change in the ability of the predators to prey on free swimming and biofilms of prey cells harboring mcr-1 was measured, as compared to their mcr-1 negative strain.
Original language | English |
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Pages (from-to) | 52-55 |
Number of pages | 4 |
Journal | Research in Microbiology |
Volume | 169 |
Issue number | 1 |
DOIs | |
Publication status | Published - 01-2018 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Microbiology
- Molecular Biology