Swine as an allotransplantation model

Takashi Kenmochi, Yoko Mullen, Masaaki Miyamoto, Elizabeth Stein

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Because of their anatomical and physiological similarities to humans, pigs are well suited for solving technical problems associated with clinical transplantation. The availability of genetically defined strains of miniature swine is unique with this species, and has permitted the investigation, in a large animal model, of immunological and genetic aspects of allograft rejection, clinical manifestations associated with bone marrow transplantation, and the feasibility of various approaches for induction of transplantation tolerance. Immunological assays and various reagents are also available in order to pursue these studies.

Original languageEnglish
Pages (from-to)177-183
Number of pages7
JournalVeterinary Immunology and Immunopathology
Volume43
Issue number1-3
DOIs
Publication statusPublished - 01-01-1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Immunology
  • veterinary(all)

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