TY - JOUR
T1 - Systemic lupus erythematosus mimicking retinal migraine
T2 - a case report
AU - Tezuka, Toshiki
AU - Shibata, Mamoru
AU - Hanaoka, Hironari
AU - Izawa, Yoshikane
AU - Kikuchi, Taku
AU - Akino, Kunihiko
AU - Ozawa, Yoko
AU - Saito, Masataka
AU - Kaneko, Yuko
AU - Nakahara, Jin
AU - Takizawa, Tsubasa
N1 - Publisher Copyright:
© International Headache Society 2023.
PY - 2023/12
Y1 - 2023/12
N2 - Background: Retinal migraine is a diagnosis of exclusion and is characterized by repeated episodes of transient monocular blindness associated with migraine. We report a case of systemic lupus erythematosus with acute episodes mimicking retinal migraines. Case report: A 46-year-old woman with a history of migraine with aura since her 20s and Evans syndrome presented with episodic transient monocular blindness. Retinal migraine was considered as the cause, and migraine prophylaxis initially reduced its frequency. After 5 months, the frequency increased, with chilblain-like lupus lesions on her extremities. Laboratory testing revealed lymphopenia and hypocomplementemia, fulfilling the diagnostic criteria for systemic lupus erythematosus, which may have caused Evans syndrome and transient monocular blindness, mimicking retinal migraines. After intravenous methylprednisolone and rituximab therapy, the transient monocular blindness episodes did not recur. Conclusion: Given the clinical presentation, systemic lupus erythematosus should be considered as a cause of transient monocular blindness and should be distinguished from retinal migraine.
AB - Background: Retinal migraine is a diagnosis of exclusion and is characterized by repeated episodes of transient monocular blindness associated with migraine. We report a case of systemic lupus erythematosus with acute episodes mimicking retinal migraines. Case report: A 46-year-old woman with a history of migraine with aura since her 20s and Evans syndrome presented with episodic transient monocular blindness. Retinal migraine was considered as the cause, and migraine prophylaxis initially reduced its frequency. After 5 months, the frequency increased, with chilblain-like lupus lesions on her extremities. Laboratory testing revealed lymphopenia and hypocomplementemia, fulfilling the diagnostic criteria for systemic lupus erythematosus, which may have caused Evans syndrome and transient monocular blindness, mimicking retinal migraines. After intravenous methylprednisolone and rituximab therapy, the transient monocular blindness episodes did not recur. Conclusion: Given the clinical presentation, systemic lupus erythematosus should be considered as a cause of transient monocular blindness and should be distinguished from retinal migraine.
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U2 - 10.1177/03331024231219477
DO - 10.1177/03331024231219477
M3 - Article
C2 - 38069834
AN - SCOPUS:85179639064
SN - 0333-1024
VL - 43
JO - Cephalalgia
JF - Cephalalgia
IS - 12
ER -