Abstract
Temperature-sensitive growth mutants of Salmonella enteritidis, NUB 209 and NUB 323, characterized as protein synthesis mutants, were unable to pro-liferate at 37 C and lost the parent's virulence. In mice, these mutants conferred high levels of protection as live vaccines. Although the vaccination effect of NUB 323 was not so good as that of NUB 209, NUB 323 was preferred as a safer live vaccine because this mutant was completely avirulent and no back mutation appeared.
| Original language | English |
|---|---|
| Pages (from-to) | 1259-1265 |
| Number of pages | 7 |
| Journal | MICROBIOLOGY and IMMUNOLOGY |
| Volume | 31 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 1987 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- Microbiology
- Immunology
- Virology
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