TY - JOUR
T1 - Ten-Year Mortality in Patients With ST-Elevation Myocardial Infarction
AU - Watanabe, Naoki
AU - Takagi, Kensuke
AU - Tanaka, Akihito
AU - Yoshioka, Naoki
AU - Morita, Yasuhiro
AU - Yoshida, Ruka
AU - Kanzaki, Yasunori
AU - Nagai, Hiroaki
AU - Yamauchi, Ryota
AU - Komeyama, Shotaro
AU - Sugiyama, Hiroki
AU - Shimojo, Kazuki
AU - Imaoka, Takuro
AU - Sakamoto, Gaku
AU - Ohi, Takuma
AU - Goto, Hiroki
AU - Okumura, Takahiro
AU - Ishii, Hideki
AU - Morishima, Itsuro
AU - Murohara, Toyoaki
N1 - Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2021/6/15
Y1 - 2021/6/15
N2 - Knowledge of the long-term prognosis (>10 years) and mortality predictors of ST-elevation myocardial infarction (STEMI) patients who have undergone primary percutaneous coronary intervention (p-PCI) is scarce. Therefore, this study evaluated the long-term prognosis and determined the predictors of long-term outcomes for STEMI patients after p-PCI. Between January, 2006 and December, 2010, we collected data and analyzed 459 consecutive patients with acute STEMI who underwent p-PCI and were discharged from the hospital (mean age, 66.8 years; male, 75.2%; peak creatine phosphokinase level, 2,292.5 IU/L). The primary endpoint was 10-year all-cause mortality. The cumulative 10-year incidence of all-cause death was 23.8%. The Cox multivariate regression analysis identified age ≥ 65 years (adjusted hazard ratio [aHR], p <0.001), body mass index (aHR, 0.93, p = 0.033), presence of atrial fibrillation (aHR, 1.69, p = 0.038), mineralocorticoid receptor antagonist use (aHR, 1.95, p = 0.008), ejection fraction <40% (aHR, 2.14, p = 0.005), and albumin <3.5 g/dL (aHR, 2.01, p = 0.005) as independent predictors of all-cause mortality. In conclusion, a post-discharge 10-year survival rate of 76.2% was identified for STEMI patients who underwent p-PCI.
AB - Knowledge of the long-term prognosis (>10 years) and mortality predictors of ST-elevation myocardial infarction (STEMI) patients who have undergone primary percutaneous coronary intervention (p-PCI) is scarce. Therefore, this study evaluated the long-term prognosis and determined the predictors of long-term outcomes for STEMI patients after p-PCI. Between January, 2006 and December, 2010, we collected data and analyzed 459 consecutive patients with acute STEMI who underwent p-PCI and were discharged from the hospital (mean age, 66.8 years; male, 75.2%; peak creatine phosphokinase level, 2,292.5 IU/L). The primary endpoint was 10-year all-cause mortality. The cumulative 10-year incidence of all-cause death was 23.8%. The Cox multivariate regression analysis identified age ≥ 65 years (adjusted hazard ratio [aHR], p <0.001), body mass index (aHR, 0.93, p = 0.033), presence of atrial fibrillation (aHR, 1.69, p = 0.038), mineralocorticoid receptor antagonist use (aHR, 1.95, p = 0.008), ejection fraction <40% (aHR, 2.14, p = 0.005), and albumin <3.5 g/dL (aHR, 2.01, p = 0.005) as independent predictors of all-cause mortality. In conclusion, a post-discharge 10-year survival rate of 76.2% was identified for STEMI patients who underwent p-PCI.
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U2 - 10.1016/j.amjcard.2021.03.008
DO - 10.1016/j.amjcard.2021.03.008
M3 - Article
C2 - 33753036
AN - SCOPUS:85104058758
SN - 0002-9149
VL - 149
SP - 9
EP - 15
JO - American Journal of Cardiology
JF - American Journal of Cardiology
ER -