TY - JOUR
T1 - Testicular cancer in father and son
AU - Ishikawa, Kiyohito
AU - Nakano, Hiroyuki
AU - Tsukamoto, Takaji
AU - Fujioka, Tosio
AU - Nagakubo, Ichiro
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1996
Y1 - 1996
N2 - The occurrence of testicular tumors in closely related family members is rare. We report a case of testicular cancers in a father and son. The father had pure seminoma, and his son developed a mixed nonseminomatous germ cell tumor. The peripheral blood lymphocytes in both patients were tested for 52 HLA specificities, and the patients were found to have six in common. The son was homozygous for HLA A24. The association between certain HLA antigens, other genetic factors, and testicular cancer requires further study to improve the care and counseling of patients and their families.
AB - The occurrence of testicular tumors in closely related family members is rare. We report a case of testicular cancers in a father and son. The father had pure seminoma, and his son developed a mixed nonseminomatous germ cell tumor. The peripheral blood lymphocytes in both patients were tested for 52 HLA specificities, and the patients were found to have six in common. The son was homozygous for HLA A24. The association between certain HLA antigens, other genetic factors, and testicular cancer requires further study to improve the care and counseling of patients and their families.
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U2 - 10.1111/j.1442-2042.1996.tb00635.x
DO - 10.1111/j.1442-2042.1996.tb00635.x
M3 - Article
C2 - 8646605
AN - SCOPUS:0029975102
SN - 0919-8172
VL - 3
SP - 70
EP - 73
JO - International Journal of Urology
JF - International Journal of Urology
IS - 1
ER -
