The Association Between Adult Height and Stroke Incidence in Japanese Men and Women: A Population-based Case-Control Study

Yoshinobu Kondo, Hiroshi Yatsuya, Atsuhiko Ota, Shoji Matsumoto, Akihiro Ueda, Hirohisa Watanabe, Hideaki Toyoshima

Research output: Contribution to journalArticlepeer-review

Abstract

Background: No studies have examined the associations between adult height and ischemic stroke subtypes. Methods: We conducted a population-based case-control study that included 2,451 thrombotic and 687 embolic stroke cases, as well as 1,623 intracerebral and 768 subarachnoid hemorrhage cases without history of stroke aged 40–79 years, and the same number of sex-and age-matched controls. Cases and controls were grouped according to the quintile cut-off values of height in controls, and the third quintile, which was approximately the average height group, was used as the reference group. Height divided by one standard deviation of height in controls was also examined as a continuous variable. The analyses were carried out separately for participants aged 40–59 years and 60–79 years. Results: In both younger and older men, height was linearly inversely associated with total and thrombotic strokes, and the shortest quintile compared to the reference group was associated with increased risks of these strokes. Although height was linearly inversely associated with embolic stroke and intracerebral hemorrhage in younger men, the shortest quintile did not show increased risks of these strokes. Height did not seem to be associated with total stroke and any stroke subtypes in younger women. In contrast, the tallest quintile was significantly associated with increased risks of total stroke and intracerebral hemorrhage, and height tended to be positively associated with these strokes in older women. Conclusion: We reported the associations between adult height and ischemic stroke subtypes for the first time, which differed according to sex and age group.

Original languageEnglish
Pages (from-to)23-30
Number of pages8
JournalJournal of epidemiology
Volume33
Issue number1
DOIs
Publication statusPublished - 2023

All Science Journal Classification (ASJC) codes

  • Epidemiology

Fingerprint

Dive into the research topics of 'The Association Between Adult Height and Stroke Incidence in Japanese Men and Women: A Population-based Case-Control Study'. Together they form a unique fingerprint.

Cite this