[The diagnosis and clinical feature of NSAIDs-associated enteritis].

Double-balloon endoscopy (DBE) is very useful for the diagnosis and treatment of non-steroidal anti-inflammatory drugs (NSAIDs)-associated enteritis. In cases of long-term NSAIDs administration, aphtha, specific diaphragm-like strictures and circular ulcers are pointed out into details by DBE. Even if on-demand use of NSAIDs, some patients have small bowel injuries when NSAIDs are administered for over several years. Moreover, there are variations for the type and indication of NSAIDs among patients. The cytolysis image and the apoptosis in the base of mucosa were reported as the characteristic histological findings of NSAIDs-associated enteritis. In consideration of widespread use of NSAIDs, a strategy for the management of NSAID-associated enteritis should be discussed and established.