The effect of the impeller-driver magnetic coupling distance on hemolysis in a compact centrifugal pump

Tadashi Nakazawa, Kenzo Makinouchi, Yoshiyuki Takami, Julie Glueck, Setsuo Takatani, Yukihiko Nosé

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Blood trauma is one of the important performance parameters of centrifugal pumps. To investigate the blood trauma induced by these pumps, in vitro hemolysis tests have become an important procedure and are increasingly used for pump development and comparisons. The Baylor compact eccentric inlet port (C1E) centrifugal blood pump was developed as a long-term centrifugal ventricular assist device (VAD) as well as-a cardiopulmonary bypass pump (CPB). The Baylor C1E pump incorporates a seal-less design with a blood stagnation-free structure. This pump can provide flows of 5 L/min against 350 mm Hg of total pressure head at 2,600 revolutions per minute. The pump impeller is magnetically coupled to the driver magnet in a seal-less manner. The latest hemolysis study revealed that hemolysis may be affected by the gap distance between the driver and the impeller magnet. The purpose of this study was to verify the effect of the magnetic coupling distance on the normalized index of hemolysis (NIH) with the C1E model and to obtain an optimal gap distance. The NIH value was clearly decreased by alteration of the magnetic coupling distance from 7.7 to 9.7 mm in CPB and left ventricular assist device (LVAD) conditions. The NIH, when using the pump as an LVAD condition, was reduced to a level of 0.0056 from 0.095 when the magnetic coupling distance was extended. The same results were also obtained when the pumps were used in a CPB condition. The magnetic coupling distance is an important factor for the C1E model in terms of hemolysis. Different coupling forces effect the bearings and impeller stability. These results suggest that an optimal driving condition with a proper magnetic coupling and an optimal force between the impeller and driver is necessary to develop an atraumatic centrifugal pump.

Original languageEnglish
Pages (from-to)252-257
Number of pages6
JournalArtificial Organs
Issue number3
Publication statusPublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering


Dive into the research topics of 'The effect of the impeller-driver magnetic coupling distance on hemolysis in a compact centrifugal pump'. Together they form a unique fingerprint.

Cite this