The Fate of Angiotensin II in Placental Tissue and Blood

Shigehiko Mizutani; Hidesuke Mizutani; Eita Mizutani; Harumasa Arita; Hiroaki Kajiyama

doi:10.1055/a-2202-3894

The Fate of Angiotensin II in Placental Tissue and Blood

Shigehiko Mizutani, Hidesuke Mizutani, Eita Mizutani, Harumasa Arita, Hiroaki Kajiyama

Research output: Contribution to journal › Review article › peer-review

Abstract

The existence of a non-canonical pathway of renin-Angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum respectively.

Original language	English
Journal	Hormone and Metabolic Research
DOIs	https://doi.org/10.1055/a-2202-3894
Publication status	Accepted/In press - 2023
Externally published	Yes

All Science Journal Classification (ASJC) codes

Endocrinology, Diabetes and Metabolism
Biochemistry
Endocrinology
Clinical Biochemistry
Biochemistry, medical

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1055/a-2202-3894

Cite this

@article{4f349e6d8f454bd9b5d0e7c0bf4b53af,

title = "The Fate of Angiotensin II in Placental Tissue and Blood",

abstract = "The existence of a non-canonical pathway of renin-Angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum respectively.",

author = "Shigehiko Mizutani and Hidesuke Mizutani and Eita Mizutani and Harumasa Arita and Hiroaki Kajiyama",

year = "2023",

doi = "10.1055/a-2202-3894",

language = "English",

journal = "Hormone and Metabolic Research",

issn = "0018-5043",

publisher = "Georg Thieme Verlag",

}

TY - JOUR

T1 - The Fate of Angiotensin II in Placental Tissue and Blood

AU - Mizutani, Shigehiko

AU - Mizutani, Hidesuke

AU - Mizutani, Eita

AU - Arita, Harumasa

AU - Kajiyama, Hiroaki

PY - 2023

Y1 - 2023

N2 - The existence of a non-canonical pathway of renin-Angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum respectively.

AB - The existence of a non-canonical pathway of renin-Angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum respectively.

UR - https://www.scopus.com/pages/publications/85176389522

UR - https://www.scopus.com/inward/citedby.url?scp=85176389522&partnerID=8YFLogxK

U2 - 10.1055/a-2202-3894

DO - 10.1055/a-2202-3894

M3 - Review article

C2 - 37913823

AN - SCOPUS:85176389522

SN - 0018-5043

JO - Hormone and Metabolic Research

JF - Hormone and Metabolic Research

ER -

The Fate of Angiotensin II in Placental Tissue and Blood

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this