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The Fate of Angiotensin II in Placental Tissue and Blood

  • Shigehiko Mizutani
  • , Hidesuke Mizutani
  • , Eita Mizutani
  • , Harumasa Arita
  • , Hiroaki Kajiyama

Research output: Contribution to journalReview articlepeer-review

Abstract

The existence of a non-canonical pathway of renin-Angiotensin system in the blood pressure control system has been highlighted over the past three decades. The enzymes involved in this pathway include a series of angiotensinases such as neprilysin (NEP), aminopeptidase A (APA), carboxypeptidase, and angiotensin converting enzyme 2. The physiological roles of these peptidases have been reconsidered in this study, based on the publications of other research groups and the results from our previous study, regarding the liberation of constituent amino acids from angiotensin II by placenta tissue and blood serum respectively.

Original languageEnglish
JournalHormone and Metabolic Research
DOIs
Publication statusAccepted/In press - 2023
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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