The non-surgical treatments of hepatocellular carcinomas in a patient with severe hemophilia A

Hidenori Toyoda, Yoshihide Fukuda, Isao Nakano, Yoshiaki Katano, Mieko Ebata, Kiyoshi Morita, Ken ichi Nagano, Shoichi Yokozaki, Mamiko Takeuchi, Kazuhiko Hayashi, Tetsuo Hayakawa, Junki Takamatsu

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

We recently treated a patient with multiple hepatocellular carcinomas (HCC) who had severe hemophilia A and thrombocytopenia secondary to cirrhosis. He was not a candidate for surgery because of his liver failure. Transcatheter arterial chemoembolization and percutaneous ethanol injection therapy were successfully performed without complications by maintaining factor VIII levels above 40%. We believe that the non-surgical treatment of HCC can be performed safely in patients with coagulation disorders, by the appropriate administration of coagulation factors, despite thrombocytopenia and/or elongation of the prothrombin time from cirrhosis.

Original languageEnglish
Pages (from-to)1156-1159
Number of pages4
JournalHepato-gastroenterology
Volume46
Issue number26
Publication statusPublished - 1999

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

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