Abstract
Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.
| Original language | English |
|---|---|
| Pages (from-to) | 169-179 |
| Number of pages | 11 |
| Journal | Fish and Shellfish Immunology |
| Volume | 12 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 01-01-2002 |
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All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Aquatic Science
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The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu. / Rahman, M. Habibur; Kuroda, Akashi; Dijkstra, Johannes M.; Kiryu, Ikunari; Nakanishi, Teruyuki; Ototake, Mitsuru.
In: Fish and Shellfish Immunology, Vol. 12, No. 2, 01.01.2002, p. 169-179.Research output: Contribution to journal › Article
TY - JOUR
T1 - The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu
AU - Rahman, M. Habibur
AU - Kuroda, Akashi
AU - Dijkstra, Johannes M.
AU - Kiryu, Ikunari
AU - Nakanishi, Teruyuki
AU - Ototake, Mitsuru
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.
AB - Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.
UR - http://www.scopus.com/inward/record.url?scp=0036166182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036166182&partnerID=8YFLogxK
U2 - 10.1006/fsim.2001.0362
DO - 10.1006/fsim.2001.0362
M3 - Article
C2 - 11911677
AN - SCOPUS:0036166182
VL - 12
SP - 169
EP - 179
JO - Fish and Shellfish Immunology
JF - Fish and Shellfish Immunology
SN - 1050-4648
IS - 2
ER -