The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

M. Habibur Rahman; Akashi Kuroda; Johannes M. Dijkstra; Ikunari Kiryu; Teruyuki Nakanishi; Mitsuru Ototake

doi:10.1006/fsim.2001.0362

The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

M. Habibur Rahman
, Akashi Kuroda
, Johannes M. Dijkstra
, Ikunari Kiryu
, Teruyuki Nakanishi
, Mitsuru Ototake

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.

Original language	English
Pages (from-to)	169-179
Number of pages	11
Journal	Fish and Shellfish Immunology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1006/fsim.2001.0362
Publication status	Published - 2002
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Immunology and Microbiology (miscellaneous)
Aquatic Science
Immunology
Environmental Chemistry

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10.1006/fsim.2001.0362

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@article{21a3c5c11f7141e1bbcef10b460dabe2,

title = "The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu",

abstract = "Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.",

author = "Rahman, \{M. Habibur\} and Akashi Kuroda and Dijkstra, \{Johannes M.\} and Ikunari Kiryu and Teruyuki Nakanishi and Mitsuru Ototake",

note = "Funding Information: The authors are thankful to Mr Yoshisuke Iida, Freshwater Fish Branch, Hiroshima Prefectural Fisheries Experiment Station, Shobara, Hiroshima 727, Japan, for providing the bacterial isolate. The authors are also grateful to the Nagano Prefectural Fisheries Experimental Station, Nagano, Japan for providing eyed eggs of rainbow trout. The first author is grateful to the Japan Ministry Education, Culture, Sports, Science and Technology for granting him a STA Post-doctoral Fellowship and thankful to the Department of Zoology, Rajshahi University, Bangladesh for granting him leave during this research. The authors gratefully thank Dr James D. Moore, Bodega Marine Laboratory, Bodega Bay, California, U.S.A., for editorial assistance with this manuscript.",

year = "2002",

doi = "10.1006/fsim.2001.0362",

language = "English",

volume = "12",

pages = "169--179",

journal = "Fish and Shellfish Immunology",

issn = "1050-4648",

publisher = "Academic Press",

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T1 - The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

AU - Rahman, M. Habibur

AU - Kuroda, Akashi

AU - Dijkstra, Johannes M.

AU - Kiryu, Ikunari

AU - Nakanishi, Teruyuki

AU - Ototake, Mitsuru

N1 - Funding Information: The authors are thankful to Mr Yoshisuke Iida, Freshwater Fish Branch, Hiroshima Prefectural Fisheries Experiment Station, Shobara, Hiroshima 727, Japan, for providing the bacterial isolate. The authors are also grateful to the Nagano Prefectural Fisheries Experimental Station, Nagano, Japan for providing eyed eggs of rainbow trout. The first author is grateful to the Japan Ministry Education, Culture, Sports, Science and Technology for granting him a STA Post-doctoral Fellowship and thankful to the Department of Zoology, Rajshahi University, Bangladesh for granting him leave during this research. The authors gratefully thank Dr James D. Moore, Bodega Marine Laboratory, Bodega Bay, California, U.S.A., for editorial assistance with this manuscript.

PY - 2002

Y1 - 2002

N2 - Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.

AB - Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.

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DO - 10.1006/fsim.2001.0362

M3 - Article

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AN - SCOPUS:0036166182

SN - 1050-4648

VL - 12

SP - 169

EP - 179

JO - Fish and Shellfish Immunology

JF - Fish and Shellfish Immunology

IS - 2

ER -

The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

Abstract

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