The preoperative nutritional assessment of surgical patients with hepatic dysfunction

Takashi Higashiguchi, Hajime Yokoi, Takashi Noguchi, Yoshifumi Kawarada, Ryuji Mizumoto, Per Olof Hasselgren

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The precise influence of malnutrition on postoperative complications in patients with hepatic dysfunction is not well known. In phase I of the present study, we evaluated the nutritional status of 102 patients with hepatic dysfunction who were admitted for elective hepatobiliary or pancreatic surgery, and a model for the prediction of postoperative complications was developed using a computer-based stepwise regression procedure. The equation for this Prognostic Nutritional Index for Surgery (PNIS) was calculated by [-0.147×(% weight change)+0.046×(% ideal body weight)+0.010×(actual triceps skinfold thickness as a % of standard value)+0.051×(hepaplastintest)]. In phase II this model was prospectively tested in 182 patients, including 145 with hepatic dysfunction. A total of 18 patients were classified as having a poor prognosis (PNIS<5) and all of these patients in fact developed postoperative complications: 128 patients were classified as having an intermediate prognosis (5≤PNIS<10), 23 (18.0%) of whom developed postoperative complications, and none of the 36 patients who were classified as having a good prognosis (PNIS≥10) developed any postoperative complications. These results demonstrate the importance of performing a thorough preoperative nutritional assessment of patients with hepatic dysfunction as malnourished patients with PNIS<10 may need preoperative nutritional management, even when their surgical procedures are not major.

Original languageEnglish
Pages (from-to)113-118
Number of pages6
JournalSurgery Today
Volume25
Issue number2
DOIs
Publication statusPublished - 01-02-1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery

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    Higashiguchi, T., Yokoi, H., Noguchi, T., Kawarada, Y., Mizumoto, R., & Hasselgren, P. O. (1995). The preoperative nutritional assessment of surgical patients with hepatic dysfunction. Surgery Today, 25(2), 113-118. https://doi.org/10.1007/BF00311081