The relationships between initial clinical features and prognosis in 14 cases of diffuse alveolar hemorrhage syndrome

Yasuo Kohashi, Yuji Saito, Yoshitaka Totani, Yukiko Yoneda, Masamichi Hayashi, Mitsushi Okazawa, Hiroki Sakakibara

Research output: Contribution to journalArticlepeer-review

Abstract

Diffuse pulmonary alveolar hemorrhage (DAH) is caused by various disorders and is a medical emergency that often results in acute respiratory failure requiring prompt diagnosis and aggressive treatment. However, the relationships between the prognosis and the initial clinical feature in DAH remain unclear. We investigated the relationships between initial clinical features and prognosis in 14 cases of DAH. We examined 14 patients with DAH about laboratory data, CT scan findings, treatment and outcome. Three of 14 patients died of acute respiratory failure due to DAH. In the laboratory data on admission, the patients with over 230 IU/L of serum LDH levels had a poor outcome. In pulmonary function data on admission, the patients with under 300 of P/F ratio had poor outcome. On CT scan findings on admission, the patients with consolidation shadows had a poor outcome compared to the patients with ground-glass shadows. In our data, serum LDH concentration, P/F ratio and CT scan findings on admission are important factors in the prognosis of DAH.

Original languageEnglish
Pages (from-to)265-270
Number of pages6
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume47
Issue number4
Publication statusPublished - 04-2009

All Science Journal Classification (ASJC) codes

  • General Medicine

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