TY - JOUR
T1 - The relationships between initial clinical features and prognosis in 14 cases of diffuse alveolar hemorrhage syndrome
AU - Kohashi, Yasuo
AU - Saito, Yuji
AU - Totani, Yoshitaka
AU - Yoneda, Yukiko
AU - Hayashi, Masamichi
AU - Okazawa, Mitsushi
AU - Sakakibara, Hiroki
PY - 2009/4
Y1 - 2009/4
N2 - Diffuse pulmonary alveolar hemorrhage (DAH) is caused by various disorders and is a medical emergency that often results in acute respiratory failure requiring prompt diagnosis and aggressive treatment. However, the relationships between the prognosis and the initial clinical feature in DAH remain unclear. We investigated the relationships between initial clinical features and prognosis in 14 cases of DAH. We examined 14 patients with DAH about laboratory data, CT scan findings, treatment and outcome. Three of 14 patients died of acute respiratory failure due to DAH. In the laboratory data on admission, the patients with over 230 IU/L of serum LDH levels had a poor outcome. In pulmonary function data on admission, the patients with under 300 of P/F ratio had poor outcome. On CT scan findings on admission, the patients with consolidation shadows had a poor outcome compared to the patients with ground-glass shadows. In our data, serum LDH concentration, P/F ratio and CT scan findings on admission are important factors in the prognosis of DAH.
AB - Diffuse pulmonary alveolar hemorrhage (DAH) is caused by various disorders and is a medical emergency that often results in acute respiratory failure requiring prompt diagnosis and aggressive treatment. However, the relationships between the prognosis and the initial clinical feature in DAH remain unclear. We investigated the relationships between initial clinical features and prognosis in 14 cases of DAH. We examined 14 patients with DAH about laboratory data, CT scan findings, treatment and outcome. Three of 14 patients died of acute respiratory failure due to DAH. In the laboratory data on admission, the patients with over 230 IU/L of serum LDH levels had a poor outcome. In pulmonary function data on admission, the patients with under 300 of P/F ratio had poor outcome. On CT scan findings on admission, the patients with consolidation shadows had a poor outcome compared to the patients with ground-glass shadows. In our data, serum LDH concentration, P/F ratio and CT scan findings on admission are important factors in the prognosis of DAH.
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M3 - Article
C2 - 19455954
AN - SCOPUS:67649405030
SN - 1343-3490
VL - 47
SP - 265
EP - 270
JO - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
JF - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
IS - 4
ER -