Abstract
Conclusion: APOBEC1 utilizes a complementing protein to select target mRNAs.
Significance: These data shed light on the selective regulation of APOBEC1 target genes.
Background: APOBEC1 stabilizes target mRNAs by suppressing nonsense- or AU-rich element-mediated decay; however, the mechanisms regulating target selection are unknown.
Results: In the presence of hnRNPQ isoform 6, APOBEC1 stabilizes interleukin-8 mRNA independently of APOBEC1 complementation factor.
| Original language | English |
|---|---|
| Pages (from-to) | 26226-26238 |
| Number of pages | 13 |
| Journal | Journal of Biological Chemistry |
| Volume | 289 |
| Issue number | 38 |
| DOIs | |
| Publication status | Published - 19-09-2014 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Molecular Biology
- Cell Biology
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