The role of selective transport in neuronal polarization

Takashi Namba, Shinichi Nakamuta, Yasuhiro Funahashi, Kozo Kaibuchi

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Neurons are functionally and morphologically polarized and possess two distinct types of neurites: axons and dendrites. Key molecules for axon formation are transported along microtubules and accumulated at the distal end of the nascent axons. In this review, we summarize recent advances in the understanding of the mechanisms involved in selective transport in neurons. In addition, we focus on motor proteins, cargo, cargo adaptors, and the loading and unloading of cargo.

Original languageEnglish
Pages (from-to)445-457
Number of pages13
JournalDevelopmental Neurobiology
Volume71
Issue number6
DOIs
Publication statusPublished - 06-2011
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Developmental Neuroscience
  • Cellular and Molecular Neuroscience

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