TY - JOUR
T1 - Therapeutic Effect of Lisuride Maleate on Post-stroke Depression
AU - Hougaku, Hidetaka
AU - Matsumoto, Masayasu
AU - Hata, Ryuji
AU - Handa, Nobuo
AU - Imaizumi, Masatoshi
AU - Sugitani, Yoshinori
AU - Yoneda, Shotaro
AU - Etani, Hideki
AU - Sueyoshi, Kenji
AU - Kusunoki, Masahito
AU - Kamada, Takenobu
AU - Uyama, Osamu
PY - 1994
Y1 - 1994
N2 - Twenty post-stroke depressive patients who obtained more than 11 points on Self-Rating Questionnaire for Depression, were treated with 0.075 mg/day lisuride maleate for 12 weeks. The drug effect on depression was evaluated quantitatively by the Hamilton Rating Scale for Depression. The relationships between brain CT or MRI and SRQ-D score were investigated in 24 subjects. More than 80% of post-stroke depressive patients improved after lisuride maleate treatment for 8 or 12 weeks. In particular, depressed mood, hypobulia, sleep disturbance, anxiety, etc. were significantly improved compared to the baseline condition. As for the relationships with CT and/or MRI findings, the group with moderate to severe brain atrophy had a significantly higher grade of depressive state than those without.
AB - Twenty post-stroke depressive patients who obtained more than 11 points on Self-Rating Questionnaire for Depression, were treated with 0.075 mg/day lisuride maleate for 12 weeks. The drug effect on depression was evaluated quantitatively by the Hamilton Rating Scale for Depression. The relationships between brain CT or MRI and SRQ-D score were investigated in 24 subjects. More than 80% of post-stroke depressive patients improved after lisuride maleate treatment for 8 or 12 weeks. In particular, depressed mood, hypobulia, sleep disturbance, anxiety, etc. were significantly improved compared to the baseline condition. As for the relationships with CT and/or MRI findings, the group with moderate to severe brain atrophy had a significantly higher grade of depressive state than those without.
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U2 - 10.3143/geriatrics.31.52
DO - 10.3143/geriatrics.31.52
M3 - Article
C2 - 8158872
AN - SCOPUS:0028268739
SN - 0300-9173
VL - 31
SP - 52
EP - 59
JO - Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
JF - Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
IS - 1
ER -