Therapeutic outcome of infectious corneal ulcers due to methicilin-resistant staphylococcus

Mari Hirano, Koji Hirano

Research output: Contribution to journalArticlepeer-review


We diagnosed 44 eyes of 44 patients as infectious corneal ulcer during 18 months through February 2004. Bacterial organisms were isolated from scrapings of the ulcer in 21 cases. Methicillin-resistant Staphylococcus aureus (MRSA) was present in 6 cases. Methicillin-resistant Staphylococcus epidermidis (MRSE) was present in 1 case. All the 7 cases were compromised hosts including advanced age, bullous keratopathy, or history of bone marrow transplantation. All the cases were cured within 3 months following treatment including frequent intillation of newquinolon and chloramphenicol. Use of vancomycin needs utmost care because of increasing incidence of vancomycin-resistant Staphylococcus aureus (VRSA) in hospitals in Japan.

Original languageEnglish
Pages (from-to)565-569
Number of pages5
JournalJapanese Journal of Clinical Ophthalmology
Issue number4
Publication statusPublished - 04-2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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