TY - JOUR
T1 - Three cases of hepatitis E infected with subgenotype 3e hepatitis E virus indigenous to Mie Prefecture, which reemerged for the first time in six years
AU - Urawa, Naohito
AU - Yoshizawa, Naohiko
AU - Kojima, Yuji
AU - Hashimoto, Akira
AU - Shimizu, Atsuya
AU - Tanaka, Takamitsu
AU - Hamaoka, Shima
AU - Kobayashi, Soichiro
AU - Nakano, Tatsunori
AU - Okano, Hiroshi
AU - Nagashima, Shigeo
AU - Takahashi, Masaharu
AU - Okamoto, Hiroaki
AU - Murata, Kazumoto
N1 - Publisher Copyright:
© 2021 The Japan Society of Hepatology.
PY - 2021/6/1
Y1 - 2021/6/1
N2 - In Mie Prefecture, autochthonous hepatitis E cases occurred via homologous hepatitis E virus subgenotype 3e (HEV-3e), namely, Mie indigenous HEV-3e, from 2004 through 2014. We experienced three cases of autochthonous hepatitis E in 2020 in Mie Prefecture, and analyzed the partial HEV genomes recovered from them. The three HEV isolates clustered with Mie indigenous HEV-3e in the phylogenetic tree and exhibited high similarities to it. Mie indigenous HEV-3e had thus reemerged for the first time in six years. One affected patient often consumed meat of wild animals, and another ate undercooked pork liver, although the third case had no clear risk factors. Mie indigenous HEV-3e appears to be maintained in wild animals or domestic pigs.
AB - In Mie Prefecture, autochthonous hepatitis E cases occurred via homologous hepatitis E virus subgenotype 3e (HEV-3e), namely, Mie indigenous HEV-3e, from 2004 through 2014. We experienced three cases of autochthonous hepatitis E in 2020 in Mie Prefecture, and analyzed the partial HEV genomes recovered from them. The three HEV isolates clustered with Mie indigenous HEV-3e in the phylogenetic tree and exhibited high similarities to it. Mie indigenous HEV-3e had thus reemerged for the first time in six years. One affected patient often consumed meat of wild animals, and another ate undercooked pork liver, although the third case had no clear risk factors. Mie indigenous HEV-3e appears to be maintained in wild animals or domestic pigs.
UR - http://www.scopus.com/inward/record.url?scp=85108648684&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85108648684&partnerID=8YFLogxK
U2 - 10.2957/kanzo.62.384
DO - 10.2957/kanzo.62.384
M3 - Article
AN - SCOPUS:85108648684
SN - 0451-4203
VL - 62
SP - 384
EP - 386
JO - Kanzo/Acta Hepatologica Japonica
JF - Kanzo/Acta Hepatologica Japonica
IS - 6
ER -