Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan

Tatsunori Nakano; Hiroshi Okano; Yoichi Nishigaki; Yusuke Suzuki; Eiichi Tomita; Makoto Kobayashi; Makoto Yamawaki; Shogo Shimizu; Koji Yamashita; Jun Ichi Sugihara; Kazuaki Takahashi; Masahiro Arai; Masaharu Takahashi; Shigeo Nagashima; Hiroaki Okamoto

doi:10.2957/kanzo.59.700

Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan

Tatsunori Nakano, Hiroshi Okano, Yoichi Nishigaki, Yusuke Suzuki, Eiichi Tomita, Makoto Kobayashi, Makoto Yamawaki, Shogo Shimizu, Koji Yamashita, Jun Ichi Sugihara, Kazuaki Takahashi, Masahiro Arai, Masaharu Takahashi, Shigeo Nagashima, Hiroaki Okamoto

Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We found three pairs of six sporadic acute hepatitis E cases infected with three different genotype 3b hepatitis E virus (HEV) strains, which were 99.7%-100% identical between two cases in each pair within the partial nucleotide sequences of ORF1 and ORF2 regions of the HEV genome. While no common source of infection was recognized within each pair, HEV infections in these cases occurred within the same economic bloc in the central region of Japan. Moreover, nucleotide sequences of the HEV strains from one pair were 99.8% identical to those obtained from pig liver sold in the same economic bloc. These results suggest the importance of continued molecular epidemiologic studies on HEV strains from humans and food products.

Original language	English
Pages (from-to)	700-703
Number of pages	4
Journal	Kanzo/Acta Hepatologica Japonica
Volume	59
Issue number	12
DOIs	https://doi.org/10.2957/kanzo.59.700
Publication status	Published - 2018

All Science Journal Classification (ASJC) codes

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2957/kanzo.59.700

Cite this

Nakano, T., Okano, H., Nishigaki, Y., Suzuki, Y., Tomita, E., Kobayashi, M., Yamawaki, M., Shimizu, S., Yamashita, K., Sugihara, J. I., Takahashi, K., Arai, M., Takahashi, M., Nagashima, S., & Okamoto, H. (2018). Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan. Kanzo/Acta Hepatologica Japonica, 59(12), 700-703. https://doi.org/10.2957/kanzo.59.700

@article{8a6068f7b4ea4d9d98b2535b00456977,

title = "Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan",

abstract = "We found three pairs of six sporadic acute hepatitis E cases infected with three different genotype 3b hepatitis E virus (HEV) strains, which were 99.7%-100% identical between two cases in each pair within the partial nucleotide sequences of ORF1 and ORF2 regions of the HEV genome. While no common source of infection was recognized within each pair, HEV infections in these cases occurred within the same economic bloc in the central region of Japan. Moreover, nucleotide sequences of the HEV strains from one pair were 99.8% identical to those obtained from pig liver sold in the same economic bloc. These results suggest the importance of continued molecular epidemiologic studies on HEV strains from humans and food products.",

author = "Tatsunori Nakano and Hiroshi Okano and Yoichi Nishigaki and Yusuke Suzuki and Eiichi Tomita and Makoto Kobayashi and Makoto Yamawaki and Shogo Shimizu and Koji Yamashita and Sugihara, {Jun Ichi} and Kazuaki Takahashi and Masahiro Arai and Masaharu Takahashi and Shigeo Nagashima and Hiroaki Okamoto",

note = "Publisher Copyright: {\textcopyright} 2018 The Japan Society of Hepatology.",

year = "2018",

doi = "10.2957/kanzo.59.700",

language = "English",

volume = "59",

pages = "700--703",

journal = "Kanzo/Acta Hepatologica Japonica",

issn = "0451-4203",

publisher = "Japan Society of Hepatology",

number = "12",

}

Nakano, T, Okano, H, Nishigaki, Y, Suzuki, Y, Tomita, E, Kobayashi, M, Yamawaki, M, Shimizu, S, Yamashita, K, Sugihara, JI, Takahashi, K, Arai, M, Takahashi, M, Nagashima, S & Okamoto, H 2018, 'Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan', Kanzo/Acta Hepatologica Japonica, vol. 59, no. 12, pp. 700-703. https://doi.org/10.2957/kanzo.59.700

Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan. / Nakano, Tatsunori; Okano, Hiroshi; Nishigaki, Yoichi et al.
In: Kanzo/Acta Hepatologica Japonica, Vol. 59, No. 12, 2018, p. 700-703.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan

AU - Nakano, Tatsunori

AU - Okano, Hiroshi

AU - Nishigaki, Yoichi

AU - Suzuki, Yusuke

AU - Tomita, Eiichi

AU - Kobayashi, Makoto

AU - Yamawaki, Makoto

AU - Shimizu, Shogo

AU - Yamashita, Koji

AU - Sugihara, Jun Ichi

AU - Takahashi, Kazuaki

AU - Arai, Masahiro

AU - Takahashi, Masaharu

AU - Nagashima, Shigeo

AU - Okamoto, Hiroaki

PY - 2018

Y1 - 2018

N2 - We found three pairs of six sporadic acute hepatitis E cases infected with three different genotype 3b hepatitis E virus (HEV) strains, which were 99.7%-100% identical between two cases in each pair within the partial nucleotide sequences of ORF1 and ORF2 regions of the HEV genome. While no common source of infection was recognized within each pair, HEV infections in these cases occurred within the same economic bloc in the central region of Japan. Moreover, nucleotide sequences of the HEV strains from one pair were 99.8% identical to those obtained from pig liver sold in the same economic bloc. These results suggest the importance of continued molecular epidemiologic studies on HEV strains from humans and food products.

AB - We found three pairs of six sporadic acute hepatitis E cases infected with three different genotype 3b hepatitis E virus (HEV) strains, which were 99.7%-100% identical between two cases in each pair within the partial nucleotide sequences of ORF1 and ORF2 regions of the HEV genome. While no common source of infection was recognized within each pair, HEV infections in these cases occurred within the same economic bloc in the central region of Japan. Moreover, nucleotide sequences of the HEV strains from one pair were 99.8% identical to those obtained from pig liver sold in the same economic bloc. These results suggest the importance of continued molecular epidemiologic studies on HEV strains from humans and food products.

UR - http://www.scopus.com/inward/record.url?scp=85063300823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063300823&partnerID=8YFLogxK

U2 - 10.2957/kanzo.59.700

DO - 10.2957/kanzo.59.700

M3 - Article

AN - SCOPUS:85063300823

SN - 0451-4203

VL - 59

SP - 700

EP - 703

JO - Kanzo/Acta Hepatologica Japonica

JF - Kanzo/Acta Hepatologica Japonica

IS - 12

ER -

Three pairs of six sporadic acute hepatitis e cases infected with three different genotype 3b hepatitis e virus strains occurred within the same economic bloc in the central region of Japan

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this