Transcranial direct current stimulation over the opercular somatosensory region does not influence experimentally induced pain: A triple blind, sham-controlled study

Soichiro Koyama, Kei Nakagawa, Satoshi Tanaka

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Transcranial magnetic stimulation (TMS) over the opercular somatosensory region (OP), which includes the secondary somatosensory cortex and the insular cortex, suppresses pain sensation. However, whether transcranial direct current stimulation (tDCS) over the OP has a similar effect on pain sensation remains unknown. We examined whether pain sensation would be suppressed by tDCS over the OP. Our experiment with a triple-blind, sham-controlled, crossover design involved 12 healthy participants. Participants were asked to rate their subjective pain intensity during and after three types of bihemispheric tDCS: right anodal/left cathodal OP tDCS, left anodal/right cathodal OP tDCS (2 mA, 12 min), and sham tDCS (15 s). Pain stimuli were alternately applied to the dorsum of each index finger using intraepidermal electrical stimulation. We observed no significant effect of tDCS over the OP on the perception of experimentally induced pain. Subjective pain intensity did not differ significantly between the three tDCS conditions. The present null results have crucial implications for the selection of optimal stimulation regions and parameters for clinical pain treatment.

Original languageEnglish
Pages (from-to)158-162
Number of pages5
JournalNeuroReport
Volume28
Issue number3
DOIs
Publication statusPublished - 01-01-2017

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Pain
Somatosensory Cortex
Transcranial Direct Current Stimulation
Transcranial Magnetic Stimulation
Cerebral Cortex
Cross-Over Studies
Electric Stimulation
Fingers
Healthy Volunteers
Therapeutics

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

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Transcranial direct current stimulation over the opercular somatosensory region does not influence experimentally induced pain : A triple blind, sham-controlled study. / Koyama, Soichiro; Nakagawa, Kei; Tanaka, Satoshi.

In: NeuroReport, Vol. 28, No. 3, 01.01.2017, p. 158-162.

Research output: Contribution to journalArticle

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