Transient splenial lesion of the corpus callosum in H1N1 influenza virus-associated encephalitis/encephalopathy

Shinji Ito, Sayuri Shima, Akihiro Ueda, Naoki Kawamura, Kunihiko Asakura, Tatsuro Mutoh

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 26-year-old man was admitted to our hospital because of high fever, drowsiness, memory disturbance, and disorientation due to H1N1 influenza virus-associated encephalitis/encephalopathy. All of his symptoms rapidly improved following methylprednisolone pulse therapy. The diffusion-weighted image of brain magnetic resonance imaging (MRI) revealed a large transient hyperintense signal lesion on the central splenium of the corpus callosum. This MRI finding in conjunction with a complete clinical recovery has been previously observed in cases of clinically mild seasonal influenza-associated encephalitis/encephalopathy, and can be also a useful clue for the diagnosis of new type of influenza, H1N1 influenza virus infection complicated by encephalitis/encephalopathy.

Original languageEnglish
Pages (from-to)915-918
Number of pages4
JournalInternal Medicine
Volume50
Issue number8
DOIs
Publication statusPublished - 06-05-2011

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H1N1 Subtype Influenza A Virus
Corpus Callosum
Brain Diseases
Encephalitis
Orthomyxoviridae
Human Influenza
Magnetic Resonance Imaging
Confusion
Sleep Stages
Methylprednisolone
Virus Diseases
Fever
Brain
Therapeutics

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Ito, Shinji ; Shima, Sayuri ; Ueda, Akihiro ; Kawamura, Naoki ; Asakura, Kunihiko ; Mutoh, Tatsuro. / Transient splenial lesion of the corpus callosum in H1N1 influenza virus-associated encephalitis/encephalopathy. In: Internal Medicine. 2011 ; Vol. 50, No. 8. pp. 915-918.
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Transient splenial lesion of the corpus callosum in H1N1 influenza virus-associated encephalitis/encephalopathy. / Ito, Shinji; Shima, Sayuri; Ueda, Akihiro; Kawamura, Naoki; Asakura, Kunihiko; Mutoh, Tatsuro.

In: Internal Medicine, Vol. 50, No. 8, 06.05.2011, p. 915-918.

Research output: Contribution to journalArticle

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