Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Yuji Yamada, Tomoo Osumi, Ken Ichi Imadome, Etsuko Takahashi, Tamae Oe, Tetsushi Yoshikawa, Daisuke Tomizawa, Motohiro Kato, Kimikazu Matsumoto

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4 Citations (Scopus)

Abstract

Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.

Original languageEnglish
Article numbere12636
JournalTransplant Infectious Disease
Volume19
Issue number1
DOIs
Publication statusPublished - 01-02-2017

All Science Journal Classification (ASJC) codes

  • Transplantation
  • Infectious Diseases

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  • Cite this

    Yamada, Y., Osumi, T., Imadome, K. I., Takahashi, E., Oe, T., Yoshikawa, T., Tomizawa, D., Kato, M., & Matsumoto, K. (2017). Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation. Transplant Infectious Disease, 19(1), [e12636]. https://doi.org/10.1111/tid.12636