Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Yuji Yamada; Tomoo Osumi; Ken Ichi Imadome; Etsuko Takahashi; Tamae Ohye; Tetsushi Yoshikawa; Daisuke Tomizawa; Motohiro Kato; Kimikazu Matsumoto

doi:10.1111/tid.12636

Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Yuji Yamada, Tomoo Osumi, Ken Ichi Imadome, Etsuko Takahashi, Tamae Ohye, Tetsushi Yoshikawa, Daisuke Tomizawa, Motohiro Kato, Kimikazu Matsumoto

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.

Original language	English
Article number	e12636
Journal	Transplant Infectious Disease
Volume	19
Issue number	1
DOIs	https://doi.org/10.1111/tid.12636
Publication status	Published - 01-02-2017

All Science Journal Classification (ASJC) codes

Transplantation
Infectious Diseases

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/tid.12636

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title = "Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation",

abstract = "Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.",

author = "Yuji Yamada and Tomoo Osumi and Imadome, {Ken Ichi} and Etsuko Takahashi and Tamae Ohye and Tetsushi Yoshikawa and Daisuke Tomizawa and Motohiro Kato and Kimikazu Matsumoto",

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AU - Yamada, Yuji

AU - Osumi, Tomoo

AU - Imadome, Ken Ichi

AU - Takahashi, Etsuko

AU - Ohye, Tamae

AU - Yoshikawa, Tetsushi

AU - Tomizawa, Daisuke

AU - Kato, Motohiro

AU - Matsumoto, Kimikazu

PY - 2017/2/1

Y1 - 2017/2/1

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AB - Chromosomally integrated human herpesvirus 6 (ciHHV-6) can be transmitted via allogeneic hematopoietic cell transplantation. To date, only a few cases have been reported. Here, we report a case identified as transmission of ciHHV-6 via cord blood transplantation. Distinguishing transmission of ciHHV-6 from HHV-6 reactivation in cases with high titer of HHV-6 DNA load after transplantation is important to prevent unnecessary exposure to antiviral drugs that could be toxic.

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Transmission of chromosomally integrated human herpesvirus 6 via cord blood transplantation

Abstract

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