Transpapillary biopsy in gallbladder disease

Yoshihiro Watanabe, Hidemi Goto, Yoshiki Hirooka, Akihiro Itoh, Tomoyuki Taki, Shinya Hayakawa, Tetsuo Hayakawa, Yasuo Naitoh, Kazuhiko Ohhashi, Kenji Yamao, Tsuyoshi Furukawa

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Background: Endoscopic biopsy is routine in gastrointestinal disease; similarly, histopathologic diagnosis is desirable in gallbladder disease. In this study we examined the clinical usefulness and the problems associated with transpapillary gallbladder biopsy. Methods: Transpapillary gallbladder biopsy was attempt ed in 9 patients with gallbladder disease. After inserting a catheter sheath into the gallbladder using a guidewire via the transpapillary route without sphincterotomy, we inserted a biopsy forceps into the lumen of the sheath up to the gallbladder lumen and obtained specimens. Results: We could obtain sufficient specimens for histopathologic diagnosis in 8 of 9 cases (88.9%). Of the 8 successful cases, targeted specimens were obtained in 7 (87.5%). Diagnostic accuracy with respect to malignant versus benign disease was 100% (2 of 2) and 83.3% (5 of 6), respectively. There were no complications. Conclusion: Transpapillary gallbladder biopsy is a clinically useful technique because it facilitates histopathologic diagnosis and therefore guides the choice of therapy.

Original languageEnglish
Pages (from-to)76-79
Number of pages4
JournalGastrointestinal endoscopy
Issue number1
Publication statusPublished - 2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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