Treatment of superior limbic keratoconjunctivitis by application of autologous serum

Eiki Goto, Shigeto Shimmura, Jun Shimazaki, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

132 Citations (Scopus)


Purpose. To determine the efficacy of autologous serum drops in the treatment of superior limbic keratoconjunctivitis (SLK). Methods. Twenty-two eyes of 11 patients were diagnosed with SLK. All eyes were treated with 20% diluted autologous serum eyedrops 10 times a day in addition to ongoing treatment of dry eye. Fluorescein and rose bengal staining scores, as well as subjective symptom gradings, were performed before and after 4 weeks of therapy. Results. Nine of the 11 patients responded well to treatment (82%). The average rose bengal and fluorescein score improved (p < 0.05), and there was subjective improvement. Conclusion. Autologous serum application can be used as an alternative mode of therapy in SLK.

Original languageEnglish
Pages (from-to)807-810
Number of pages4
Issue number8
Publication statusPublished - 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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