Treatment option and pitfalls for skull base meningiomas

Mitsuhiro Hasegawa, Mitsutoshi Nakada, Naoyuki Uchiyama, Hironori Fujisawa, Yasuo Tohma, Yutaka Hayashi, Junkoh Yamashita

Research output: Contribution to journalArticlepeer-review


Advances in skull base surgical techniques and radiosurgery have led to significant improvements in the treatment of skull base meningioma. However, as the natural history and the biological behavior of skull base meningiomas are not well known, the selection of and timing for postoperative additional treatment are still controversial. Herein we discuss our experiences in the treatment of skull base meningiomas, the natural history together with a literature review, and the invasion-related factors, especially matrix metalloproteinases (MMPs), for use as a new biological marker for skull base meningiomas.

Original languageEnglish
Pages (from-to)396-402
Number of pages7
JournalJapanese Journal of Neurosurgery
Issue number5
Publication statusPublished - 05-2006

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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