Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer

Sho Shimohama; Koichi Oki; Hidefumi Narita; Kyoko Mashima; Satoshi Yamada; Tomohide Adachi; Yosuke Kobayashi; Shigemichi Hirose; Haruhiko Hoshino

doi:10.2169/internalmedicine.7477-21

Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer

Sho Shimohama, Koichi Oki, Hidefumi Narita, Kyoko Mashima, Satoshi Yamada, Tomohide Adachi, Yosuke Kobayashi, Shigemichi Hirose, Haruhiko Hoshino

Gastrointestinal Surgery

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations.

Original language	English
Pages (from-to)	97-101
Number of pages	5
Journal	Internal Medicine
Volume	61
Issue number	1
DOIs	https://doi.org/10.2169/internalmedicine.7477-21
Publication status	Published - 2022

All Science Journal Classification (ASJC) codes

Internal Medicine

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abstract = "We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations.",

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AU - Shimohama, Sho

AU - Oki, Koichi

AU - Narita, Hidefumi

AU - Mashima, Kyoko

AU - Yamada, Satoshi

AU - Adachi, Tomohide

AU - Kobayashi, Yosuke

AU - Hirose, Shigemichi

AU - Hoshino, Haruhiko

PY - 2022

Y1 - 2022

N2 - We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations.

AB - We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations.

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Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer

Abstract

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