Two cases of Stevens-Johnson syndrome analyzed for HLA

Masamichi Abe; Mamiko Nakagawa; Kayoko Matsunaga; Akiko Yagami; Akiyo Sano

Two cases of Stevens-Johnson syndrome analyzed for HLA

Masamichi Abe, Mamiko Nakagawa, Kayoko Matsunaga, Akiko Yagami, Akiyo Sano

integrative medical science for allergic disease

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Abstract

We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.

Original language	English
Pages (from-to)	158-163
Number of pages	6
Journal	skin research
Volume	8
Issue number	2
Publication status	Published - 04-2009

All Science Journal Classification (ASJC) codes

Dermatology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Two cases of Stevens-Johnson syndrome analyzed for HLA",

abstract = "We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.",

author = "Masamichi Abe and Mamiko Nakagawa and Kayoko Matsunaga and Akiko Yagami and Akiyo Sano",

year = "2009",

month = apr,

language = "English",

volume = "8",

pages = "158--163",

journal = "skin research",

issn = "1347-1813",

publisher = "Osaka University",

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T1 - Two cases of Stevens-Johnson syndrome analyzed for HLA

AU - Abe, Masamichi

AU - Nakagawa, Mamiko

AU - Matsunaga, Kayoko

AU - Yagami, Akiko

AU - Sano, Akiyo

PY - 2009/4

Y1 - 2009/4

N2 - We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.

AB - We report two Japanese patients with Stevens-Johnson syndrome (SJS) who were investigated for HLA gene markers associated with SJS and toxic epidermal necrolysis. Patient 1 was a 53-year-old woman. She developed eruptions in oral provocation tests and was diagnosed with SJS due to allopurinol, clarithromycin, and loxoprofen sodium. Gene analysis revealed HLA-B*5801. Patient 2 was a 54-year-old man. He was positive on a carbamazepine patch test and drug-induced lymphocyte stimulation test, and was diagnosed with SJS due to carbamazepine. HLA-B*1502 was not detected on gene analysis.

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M3 - Article

AN - SCOPUS:72849146720

SN - 1347-1813

VL - 8

SP - 158

EP - 163

JO - skin research

JF - skin research

IS - 2

ER -

Two cases of Stevens-Johnson syndrome analyzed for HLA

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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