Type 1 diabetes mellitus and klinefelter syndrome

Teruaki Sakurai; Katsumi Iizuka; Takehiro Kato; Jun Takeda

doi:10.2169/internalmedicine.1051-18

Type 1 diabetes mellitus and klinefelter syndrome

Teruaki Sakurai
, Katsumi Iizuka
, Takehiro Kato
, Jun Takeda

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A 60-year-old male patient with type 1 diabetes mellitus (T1DM) was admitted for glycemic control. The patient exhibited abdominal adiposity, osteoporosis, and high insulin requirement (>100 U), and we suspected hypogonadism. A physical examination revealed small testes and thin pubic hair, laboratory examination found high luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels and low testosterone levels, and a chromosome analysis (47, XXY) indicated hypogonadism due to Klinefelter syndrome (KS). KS is associated with autoimmune diseases and patients positive for diabetes related auto-antibodies. In male patients with T1DM and abdominal adiposity, the concurrence of KS should be taken into consideration.

Original language	English
Pages (from-to)	259-262
Number of pages	4
Journal	Internal Medicine
Volume	58
Issue number	2
DOIs	https://doi.org/10.2169/internalmedicine.1051-18
Publication status	Published - 15-01-2019
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Internal Medicine

Access to Document

10.2169/internalmedicine.1051-18

Cite this

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title = "Type 1 diabetes mellitus and klinefelter syndrome",

abstract = "A 60-year-old male patient with type 1 diabetes mellitus (T1DM) was admitted for glycemic control. The patient exhibited abdominal adiposity, osteoporosis, and high insulin requirement (>100 U), and we suspected hypogonadism. A physical examination revealed small testes and thin pubic hair, laboratory examination found high luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels and low testosterone levels, and a chromosome analysis (47, XXY) indicated hypogonadism due to Klinefelter syndrome (KS). KS is associated with autoimmune diseases and patients positive for diabetes related auto-antibodies. In male patients with T1DM and abdominal adiposity, the concurrence of KS should be taken into consideration.",

keywords = "Abdominal adiposity, Klinefelter syndrome (KS), Osteoporosis, Type 1 diabetes mellitus (T1DM)",

author = "Teruaki Sakurai and Katsumi Iizuka and Takehiro Kato and Jun Takeda",

note = "Publisher Copyright: {\textcopyright} 2019 The Japanese Society of Internal Medicine.",

year = "2019",

month = jan,

day = "15",

doi = "10.2169/internalmedicine.1051-18",

language = "English",

volume = "58",

pages = "259--262",

journal = "Internal Medicine",

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}

TY - JOUR

T1 - Type 1 diabetes mellitus and klinefelter syndrome

AU - Sakurai, Teruaki

AU - Iizuka, Katsumi

AU - Kato, Takehiro

AU - Takeda, Jun

PY - 2019/1/15

Y1 - 2019/1/15

N2 - A 60-year-old male patient with type 1 diabetes mellitus (T1DM) was admitted for glycemic control. The patient exhibited abdominal adiposity, osteoporosis, and high insulin requirement (>100 U), and we suspected hypogonadism. A physical examination revealed small testes and thin pubic hair, laboratory examination found high luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels and low testosterone levels, and a chromosome analysis (47, XXY) indicated hypogonadism due to Klinefelter syndrome (KS). KS is associated with autoimmune diseases and patients positive for diabetes related auto-antibodies. In male patients with T1DM and abdominal adiposity, the concurrence of KS should be taken into consideration.

AB - A 60-year-old male patient with type 1 diabetes mellitus (T1DM) was admitted for glycemic control. The patient exhibited abdominal adiposity, osteoporosis, and high insulin requirement (>100 U), and we suspected hypogonadism. A physical examination revealed small testes and thin pubic hair, laboratory examination found high luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels and low testosterone levels, and a chromosome analysis (47, XXY) indicated hypogonadism due to Klinefelter syndrome (KS). KS is associated with autoimmune diseases and patients positive for diabetes related auto-antibodies. In male patients with T1DM and abdominal adiposity, the concurrence of KS should be taken into consideration.

KW - Abdominal adiposity

KW - Klinefelter syndrome (KS)

KW - Osteoporosis

KW - Type 1 diabetes mellitus (T1DM)

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UR - https://www.scopus.com/pages/publications/85060024416#tab=citedBy

U2 - 10.2169/internalmedicine.1051-18

DO - 10.2169/internalmedicine.1051-18

M3 - Article

C2 - 30146555

AN - SCOPUS:85060024416

SN - 0918-2918

VL - 58

SP - 259

EP - 262

JO - Internal Medicine

JF - Internal Medicine

IS - 2

ER -

Type 1 diabetes mellitus and klinefelter syndrome

Abstract

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All Science Journal Classification (ASJC) codes

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