TY - JOUR
T1 - Undifferentiated carcinoma of the broad ligament in a 28-year-old woman - A case report and results of immunohistochemical and electron-microscopic studies
AU - Kobayashi, Yoichi
AU - Yamazaki, Kazuto
AU - Shinohara, Masami
AU - Iwahashi, Kazuhiro
AU - Suzuki, Atsushi
AU - Fujii, Takuma
AU - Sasaki, Hirosuke
AU - Shiraishi, Satoru
PY - 1996/12
Y1 - 1996/12
N2 - A case of undifferentiated carcinoma of the broad ligament is reported. The patient was a 28-year-old Japanese woman who underwent laparotomy for a cystic and solid tumor of the left broad ligament. The tumor measured 9 cm in diameter and was unattached to the uterus, ipsilateral ovary, or salpinx. Histological examination revealed tumor tissue consisting of solid nests of irregular configuration and rather small to medium-sized undifferentiated epithelial cells. The tumor cells were positive for cytokeratin, but negative for CA125, epithelial membrane antigen, S-100 protein, amylase, carcinoembryonic antigen, chromogranin A, synaptophysin, HHF35, desmin, and vimentin. Electron-microscopic examination revealed gap junctions and primitive cellular junctions, but no intracytoplasmic mucous granules or microvilli on the surface of the tumor cells. This is the first report of undifferentiated carcinoma of the broad ligament as far as we have been able to determine from a search of the literature.
AB - A case of undifferentiated carcinoma of the broad ligament is reported. The patient was a 28-year-old Japanese woman who underwent laparotomy for a cystic and solid tumor of the left broad ligament. The tumor measured 9 cm in diameter and was unattached to the uterus, ipsilateral ovary, or salpinx. Histological examination revealed tumor tissue consisting of solid nests of irregular configuration and rather small to medium-sized undifferentiated epithelial cells. The tumor cells were positive for cytokeratin, but negative for CA125, epithelial membrane antigen, S-100 protein, amylase, carcinoembryonic antigen, chromogranin A, synaptophysin, HHF35, desmin, and vimentin. Electron-microscopic examination revealed gap junctions and primitive cellular junctions, but no intracytoplasmic mucous granules or microvilli on the surface of the tumor cells. This is the first report of undifferentiated carcinoma of the broad ligament as far as we have been able to determine from a search of the literature.
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U2 - 10.1006/gyno.1996.0340
DO - 10.1006/gyno.1996.0340
M3 - Article
C2 - 8946876
AN - SCOPUS:0030561527
SN - 0090-8258
VL - 63
SP - 382
EP - 387
JO - Gynecologic oncology
JF - Gynecologic oncology
IS - 3
ER -