Undifferentiated carcinoma of the broad ligament in a 28-year-old woman - A case report and results of immunohistochemical and electron-microscopic studies

Yoichi Kobayashi, Kazuto Yamazaki, Masami Shinohara, Kazuhiro Iwahashi, Atsushi Suzuki, Takuma Fujii, Hirosuke Sasaki, Satoru Shiraishi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A case of undifferentiated carcinoma of the broad ligament is reported. The patient was a 28-year-old Japanese woman who underwent laparotomy for a cystic and solid tumor of the left broad ligament. The tumor measured 9 cm in diameter and was unattached to the uterus, ipsilateral ovary, or salpinx. Histological examination revealed tumor tissue consisting of solid nests of irregular configuration and rather small to medium-sized undifferentiated epithelial cells. The tumor cells were positive for cytokeratin, but negative for CA125, epithelial membrane antigen, S-100 protein, amylase, carcinoembryonic antigen, chromogranin A, synaptophysin, HHF35, desmin, and vimentin. Electron-microscopic examination revealed gap junctions and primitive cellular junctions, but no intracytoplasmic mucous granules or microvilli on the surface of the tumor cells. This is the first report of undifferentiated carcinoma of the broad ligament as far as we have been able to determine from a search of the literature.

Original languageEnglish
Pages (from-to)382-387
Number of pages6
JournalGynecologic Oncology
Volume63
Issue number3
DOIs
Publication statusPublished - 01-01-1996
Externally publishedYes

Fingerprint

Broad Ligament
Electrons
Carcinoma
S100 Proteins
Neoplasms
Chromogranin A
Mucin-1
Synaptophysin
Desmin
Fallopian Tubes
Gap Junctions
Carcinoembryonic Antigen
Vimentin
Amylases
Microvilli
Keratins
Laparotomy
Uterus
Ovary
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

Kobayashi, Yoichi ; Yamazaki, Kazuto ; Shinohara, Masami ; Iwahashi, Kazuhiro ; Suzuki, Atsushi ; Fujii, Takuma ; Sasaki, Hirosuke ; Shiraishi, Satoru. / Undifferentiated carcinoma of the broad ligament in a 28-year-old woman - A case report and results of immunohistochemical and electron-microscopic studies. In: Gynecologic Oncology. 1996 ; Vol. 63, No. 3. pp. 382-387.
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Undifferentiated carcinoma of the broad ligament in a 28-year-old woman - A case report and results of immunohistochemical and electron-microscopic studies. / Kobayashi, Yoichi; Yamazaki, Kazuto; Shinohara, Masami; Iwahashi, Kazuhiro; Suzuki, Atsushi; Fujii, Takuma; Sasaki, Hirosuke; Shiraishi, Satoru.

In: Gynecologic Oncology, Vol. 63, No. 3, 01.01.1996, p. 382-387.

Research output: Contribution to journalArticle

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