Unusual mono-reassortant of a Wa-like G1P[8] species A rotavirus containing a DS-1-like (genotype 2) NSP4 gene

Tung Phan, Tomihiko Ide, Satoshi Komoto, Pattara Khamrin, Shoko Okitsu, Koki Taniguchi, Hideaki Kikuta, Niwat Maneekarn, Satoshi Hayakawa, Hiroshi Ushijima

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1 Citation (Scopus)

Abstract

Species A rotaviruses are a major cause of acute gastroenteritis in infants and young children worldwide. Reassortment is a common phenomenon due to the segmented nature of the rotavirus genome. The complete coding sequences of a species A rotavirus strain isolated from the feces of a child with acute gastroenteritis in Japan in 2018 were determined using an unbiased viral metagenomics approach. The genetic analysis revealed that the rotavirus strain had an unusual genomic constellation (G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E2-H1), suggesting reassortment of a genotype 1 with a genotype 2 rotavirus, from which the NSP4-encoding gene was acquired.

Original languageEnglish
Pages (from-to)638-641
Number of pages4
JournalVirus Genes
Volume56
Issue number5
DOIs
Publication statusPublished - 01-10-2020

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Virology

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