Use of capsule endoscopy in patients with Crohn's disease in Japan: A multicenter survey

Motohiro Esaki, Takayuki Matsumoto, Kenji Watanabe, Tetsuo Arakawa, Yuji Naito, Minoru Matsuura, Hiroshi Nakase, Toshifumi Hibi, Takayuki Matsumoto, Sadaharu Nouda, Kazuhide Higuchi, Naoki Ohmiya, Hidemi Goto, Sei Kurokawa, Satoshi Motoya, Mamoru Watanabe

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Background and Aim: Until the approval of patency capsule, capsule endoscopy (CE) has not been routinely applied for the diagnosis of Crohn's disease (CD) in Japan. We aimed to survey current situation of CE use for patients with CD in Japan. Methods: The nationwide survey of 40 Japanese institutions identified 94 patients with established CD (eCD) and 80 patients with suspected CD (sCD), who were examined by CE. Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In sCD, final diagnosis after CE was also analyzed. Results: Patients with eCD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with eCD of colitis type had ileal lesions under CE, thereby being reclassified as ileocolitis type. In patients with sCD, CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with sCD, who were diagnosed as not having CD. Capsule retention rate was not statistically different between patients with eCD and those with sCD (7.4% vs 6.3%, P=1.0). Conclusions: CE is useful for the evaluation of small bowel mucosal injuries in Japanese patients with sCD and eCD. Possible intestinal stricture needs to be carefully evaluated before CE even in patients with sCD.

Original languageEnglish
Pages (from-to)96-101
Number of pages6
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume29
Issue number1
DOIs
Publication statusPublished - 01-01-2014

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Capsule Endoscopy
Crohn Disease
Japan
Capsules
Surveys and Questionnaires
Wounds and Injuries
Colitis
Ileitis

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Esaki, M., Matsumoto, T., Watanabe, K., Arakawa, T., Naito, Y., Matsuura, M., ... Watanabe, M. (2014). Use of capsule endoscopy in patients with Crohn's disease in Japan: A multicenter survey. Journal of Gastroenterology and Hepatology (Australia), 29(1), 96-101. https://doi.org/10.1111/jgh.12411
Esaki, Motohiro ; Matsumoto, Takayuki ; Watanabe, Kenji ; Arakawa, Tetsuo ; Naito, Yuji ; Matsuura, Minoru ; Nakase, Hiroshi ; Hibi, Toshifumi ; Matsumoto, Takayuki ; Nouda, Sadaharu ; Higuchi, Kazuhide ; Ohmiya, Naoki ; Goto, Hidemi ; Kurokawa, Sei ; Motoya, Satoshi ; Watanabe, Mamoru. / Use of capsule endoscopy in patients with Crohn's disease in Japan : A multicenter survey. In: Journal of Gastroenterology and Hepatology (Australia). 2014 ; Vol. 29, No. 1. pp. 96-101.
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abstract = "Background and Aim: Until the approval of patency capsule, capsule endoscopy (CE) has not been routinely applied for the diagnosis of Crohn's disease (CD) in Japan. We aimed to survey current situation of CE use for patients with CD in Japan. Methods: The nationwide survey of 40 Japanese institutions identified 94 patients with established CD (eCD) and 80 patients with suspected CD (sCD), who were examined by CE. Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In sCD, final diagnosis after CE was also analyzed. Results: Patients with eCD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with eCD of colitis type had ileal lesions under CE, thereby being reclassified as ileocolitis type. In patients with sCD, CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with sCD, who were diagnosed as not having CD. Capsule retention rate was not statistically different between patients with eCD and those with sCD (7.4{\%} vs 6.3{\%}, P=1.0). Conclusions: CE is useful for the evaluation of small bowel mucosal injuries in Japanese patients with sCD and eCD. Possible intestinal stricture needs to be carefully evaluated before CE even in patients with sCD.",
author = "Motohiro Esaki and Takayuki Matsumoto and Kenji Watanabe and Tetsuo Arakawa and Yuji Naito and Minoru Matsuura and Hiroshi Nakase and Toshifumi Hibi and Takayuki Matsumoto and Sadaharu Nouda and Kazuhide Higuchi and Naoki Ohmiya and Hidemi Goto and Sei Kurokawa and Satoshi Motoya and Mamoru Watanabe",
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Esaki, M, Matsumoto, T, Watanabe, K, Arakawa, T, Naito, Y, Matsuura, M, Nakase, H, Hibi, T, Matsumoto, T, Nouda, S, Higuchi, K, Ohmiya, N, Goto, H, Kurokawa, S, Motoya, S & Watanabe, M 2014, 'Use of capsule endoscopy in patients with Crohn's disease in Japan: A multicenter survey', Journal of Gastroenterology and Hepatology (Australia), vol. 29, no. 1, pp. 96-101. https://doi.org/10.1111/jgh.12411

Use of capsule endoscopy in patients with Crohn's disease in Japan : A multicenter survey. / Esaki, Motohiro; Matsumoto, Takayuki; Watanabe, Kenji; Arakawa, Tetsuo; Naito, Yuji; Matsuura, Minoru; Nakase, Hiroshi; Hibi, Toshifumi; Matsumoto, Takayuki; Nouda, Sadaharu; Higuchi, Kazuhide; Ohmiya, Naoki; Goto, Hidemi; Kurokawa, Sei; Motoya, Satoshi; Watanabe, Mamoru.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 29, No. 1, 01.01.2014, p. 96-101.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Use of capsule endoscopy in patients with Crohn's disease in Japan

T2 - A multicenter survey

AU - Esaki, Motohiro

AU - Matsumoto, Takayuki

AU - Watanabe, Kenji

AU - Arakawa, Tetsuo

AU - Naito, Yuji

AU - Matsuura, Minoru

AU - Nakase, Hiroshi

AU - Hibi, Toshifumi

AU - Matsumoto, Takayuki

AU - Nouda, Sadaharu

AU - Higuchi, Kazuhide

AU - Ohmiya, Naoki

AU - Goto, Hidemi

AU - Kurokawa, Sei

AU - Motoya, Satoshi

AU - Watanabe, Mamoru

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Background and Aim: Until the approval of patency capsule, capsule endoscopy (CE) has not been routinely applied for the diagnosis of Crohn's disease (CD) in Japan. We aimed to survey current situation of CE use for patients with CD in Japan. Methods: The nationwide survey of 40 Japanese institutions identified 94 patients with established CD (eCD) and 80 patients with suspected CD (sCD), who were examined by CE. Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In sCD, final diagnosis after CE was also analyzed. Results: Patients with eCD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with eCD of colitis type had ileal lesions under CE, thereby being reclassified as ileocolitis type. In patients with sCD, CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with sCD, who were diagnosed as not having CD. Capsule retention rate was not statistically different between patients with eCD and those with sCD (7.4% vs 6.3%, P=1.0). Conclusions: CE is useful for the evaluation of small bowel mucosal injuries in Japanese patients with sCD and eCD. Possible intestinal stricture needs to be carefully evaluated before CE even in patients with sCD.

AB - Background and Aim: Until the approval of patency capsule, capsule endoscopy (CE) has not been routinely applied for the diagnosis of Crohn's disease (CD) in Japan. We aimed to survey current situation of CE use for patients with CD in Japan. Methods: The nationwide survey of 40 Japanese institutions identified 94 patients with established CD (eCD) and 80 patients with suspected CD (sCD), who were examined by CE. Types and positive rates of mucosal injury under CE and capsule retention rate were investigated. In sCD, final diagnosis after CE was also analyzed. Results: Patients with eCD comprised 82 patients of ileitis or ileocolitis type, while 12 patients had CD of colitis type. CE identified mucosal injuries in 83 of 94 patients. Eight of 12 patients with eCD of colitis type had ileal lesions under CE, thereby being reclassified as ileocolitis type. In patients with sCD, CE detected mucosal injuries in 58 patients. Linear ulceration and cobblestone appearance were depicted in 22 and 3 patients, respectively, thereby resulting in established diagnosis of CD in 23 patients. Mucosal lesion was not found in 22 patients with sCD, who were diagnosed as not having CD. Capsule retention rate was not statistically different between patients with eCD and those with sCD (7.4% vs 6.3%, P=1.0). Conclusions: CE is useful for the evaluation of small bowel mucosal injuries in Japanese patients with sCD and eCD. Possible intestinal stricture needs to be carefully evaluated before CE even in patients with sCD.

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