Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer

Y. Otsuka, Y. Niwa, N. Ohmiya, N. Ando, A. Ohashi, Y. Hirooka, H. Goto

Research output: Contribution to journalArticle

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Abstract

Background and study aims: We investigated the characteristic findings of early gastric cancer revealed by magnifying endoscopy, and clarified their relationship with histopathological features. Patients and methods: A total of 74 patients with early gastric cancer underwent magnifying endoscopy (× 80) between March 2000 and December 2001. The endoscopic findings demonstrated 11 elevated-type carcinomas and 63 depressed-type, and histological examination showed 56 differentiated carcinomas and 18 undifferentiated carcinomas. The histopathological results were compared with findings from magnifying endoscopy regarding minute surface structure and microvessels. Results: We were able to roughly classify the minute surface structure of early gastric cancer as shown by magnifying endoscopy into three patterns, as follows: (i) a small regular pattern of sulci and ridges; (ii) an irregular pattern of sulci and ridges; and (iii) a lack of visible structure. Abnormal microvessels observed in cancerous lesions were classified according to two patterns: irregular minute vessels and variation of vessel caliber. The small regular pattern of sulci and ridges was significantly more frequently observed in differentiated carcinoma (30/56, 53.6%) than in undifferentiated carcinoma (2/18, 11.1 %). Lack of visible structure and irregular minute vessels were significantly more frequently observed in undifferentiated carcinoma (44.4% and 77.7%) than in differentiated carcinomas (5.4% and 51.8%). Conclusion: The minute surface structure and microvessels observed by magnifying endoscopy were related to histopathological findings. Magnifying endoscopy is valuable for predicting the histological nature in the diagnosis of early gastric cancer.

Original languageEnglish
Pages (from-to)165-169
Number of pages5
JournalEndoscopy
Volume36
Issue number2
DOIs
Publication statusPublished - 01-02-2004
Externally publishedYes

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Endoscopy
Stomach Neoplasms
Carcinoma
Microvessels

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Otsuka, Y., Niwa, Y., Ohmiya, N., Ando, N., Ohashi, A., Hirooka, Y., & Goto, H. (2004). Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer. Endoscopy, 36(2), 165-169. https://doi.org/10.1055/s-2004-814184
Otsuka, Y. ; Niwa, Y. ; Ohmiya, N. ; Ando, N. ; Ohashi, A. ; Hirooka, Y. ; Goto, H. / Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer. In: Endoscopy. 2004 ; Vol. 36, No. 2. pp. 165-169.
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abstract = "Background and study aims: We investigated the characteristic findings of early gastric cancer revealed by magnifying endoscopy, and clarified their relationship with histopathological features. Patients and methods: A total of 74 patients with early gastric cancer underwent magnifying endoscopy (× 80) between March 2000 and December 2001. The endoscopic findings demonstrated 11 elevated-type carcinomas and 63 depressed-type, and histological examination showed 56 differentiated carcinomas and 18 undifferentiated carcinomas. The histopathological results were compared with findings from magnifying endoscopy regarding minute surface structure and microvessels. Results: We were able to roughly classify the minute surface structure of early gastric cancer as shown by magnifying endoscopy into three patterns, as follows: (i) a small regular pattern of sulci and ridges; (ii) an irregular pattern of sulci and ridges; and (iii) a lack of visible structure. Abnormal microvessels observed in cancerous lesions were classified according to two patterns: irregular minute vessels and variation of vessel caliber. The small regular pattern of sulci and ridges was significantly more frequently observed in differentiated carcinoma (30/56, 53.6{\%}) than in undifferentiated carcinoma (2/18, 11.1 {\%}). Lack of visible structure and irregular minute vessels were significantly more frequently observed in undifferentiated carcinoma (44.4{\%} and 77.7{\%}) than in differentiated carcinomas (5.4{\%} and 51.8{\%}). Conclusion: The minute surface structure and microvessels observed by magnifying endoscopy were related to histopathological findings. Magnifying endoscopy is valuable for predicting the histological nature in the diagnosis of early gastric cancer.",
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Otsuka, Y, Niwa, Y, Ohmiya, N, Ando, N, Ohashi, A, Hirooka, Y & Goto, H 2004, 'Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer', Endoscopy, vol. 36, no. 2, pp. 165-169. https://doi.org/10.1055/s-2004-814184

Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer. / Otsuka, Y.; Niwa, Y.; Ohmiya, N.; Ando, N.; Ohashi, A.; Hirooka, Y.; Goto, H.

In: Endoscopy, Vol. 36, No. 2, 01.02.2004, p. 165-169.

Research output: Contribution to journalArticle

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T1 - Usefulness of magnifying endoscopy in the diagnosis of early gastric cancer

AU - Otsuka, Y.

AU - Niwa, Y.

AU - Ohmiya, N.

AU - Ando, N.

AU - Ohashi, A.

AU - Hirooka, Y.

AU - Goto, H.

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N2 - Background and study aims: We investigated the characteristic findings of early gastric cancer revealed by magnifying endoscopy, and clarified their relationship with histopathological features. Patients and methods: A total of 74 patients with early gastric cancer underwent magnifying endoscopy (× 80) between March 2000 and December 2001. The endoscopic findings demonstrated 11 elevated-type carcinomas and 63 depressed-type, and histological examination showed 56 differentiated carcinomas and 18 undifferentiated carcinomas. The histopathological results were compared with findings from magnifying endoscopy regarding minute surface structure and microvessels. Results: We were able to roughly classify the minute surface structure of early gastric cancer as shown by magnifying endoscopy into three patterns, as follows: (i) a small regular pattern of sulci and ridges; (ii) an irregular pattern of sulci and ridges; and (iii) a lack of visible structure. Abnormal microvessels observed in cancerous lesions were classified according to two patterns: irregular minute vessels and variation of vessel caliber. The small regular pattern of sulci and ridges was significantly more frequently observed in differentiated carcinoma (30/56, 53.6%) than in undifferentiated carcinoma (2/18, 11.1 %). Lack of visible structure and irregular minute vessels were significantly more frequently observed in undifferentiated carcinoma (44.4% and 77.7%) than in differentiated carcinomas (5.4% and 51.8%). Conclusion: The minute surface structure and microvessels observed by magnifying endoscopy were related to histopathological findings. Magnifying endoscopy is valuable for predicting the histological nature in the diagnosis of early gastric cancer.

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