Usefulness of magnifying narrow-band imaging endoscopy in the helicobacter pylori-related chronic gastritis

Masaaki Okubo, Tomomitsu Tahara, Tomoyuki Shibata, Masakatsu Nakamura, Yoshio Kamiya, Daisuke Yoshioka, Yoshiteru Maeda, Joh Yonemura, Takamitsu Ishizuka, Tomiyasu Arisawa, Ichiro Hirata

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Combining the narrow-band imaging (NBI) system and magnifying endoscopy allows simple and clear visualization of microscopic structures of the superficial mucosa and its capillary patterns, which may be useful for precise endoscopic diagnosis in the gastrointestinal tract, being more closely to histopathological diagnosis. In the non-neoplastic gastric mucosa, there have been reports showing a potential usefulness of magnifying NBI for the diagnosis of Helicobacter pylori infection, degree of histological gastritis, and intestinal metaplasia. We have shown that magnifying NBI appearances in the non-neoplastic gastric mucosa also predicts pepsinogen levels, which indicates extension of gastric atrophy in the entire stomach, and gastric cancer occurrence. Furthermore, we have shown that magnifying NBI appearances predicts the result of H. pylori treatment. Clear visualization of fine mucosal and capillary patterns, obtained by magnifying NBI, allows prediction of the histological condition, more in detail without biopsy, and it may also be useful for less invasive, and cost-effective endoscopic gastric cancer surveillance, and prediction of H. pylori eradication.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalDigestion
Volume83
Issue number3
DOIs
Publication statusPublished - 01-01-2011

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Narrow Band Imaging
Gastritis
Helicobacter pylori
Endoscopy
Stomach Neoplasms
Gastric Mucosa
Pepsinogen A
Metaplasia
Helicobacter Infections
Atrophy
Gastrointestinal Tract
Stomach
Mucous Membrane
Biopsy
Costs and Cost Analysis

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Okubo, Masaaki ; Tahara, Tomomitsu ; Shibata, Tomoyuki ; Nakamura, Masakatsu ; Kamiya, Yoshio ; Yoshioka, Daisuke ; Maeda, Yoshiteru ; Yonemura, Joh ; Ishizuka, Takamitsu ; Arisawa, Tomiyasu ; Hirata, Ichiro. / Usefulness of magnifying narrow-band imaging endoscopy in the helicobacter pylori-related chronic gastritis. In: Digestion. 2011 ; Vol. 83, No. 3. pp. 161-166.
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Okubo, M, Tahara, T, Shibata, T, Nakamura, M, Kamiya, Y, Yoshioka, D, Maeda, Y, Yonemura, J, Ishizuka, T, Arisawa, T & Hirata, I 2011, 'Usefulness of magnifying narrow-band imaging endoscopy in the helicobacter pylori-related chronic gastritis', Digestion, vol. 83, no. 3, pp. 161-166. https://doi.org/10.1159/000321799

Usefulness of magnifying narrow-band imaging endoscopy in the helicobacter pylori-related chronic gastritis. / Okubo, Masaaki; Tahara, Tomomitsu; Shibata, Tomoyuki; Nakamura, Masakatsu; Kamiya, Yoshio; Yoshioka, Daisuke; Maeda, Yoshiteru; Yonemura, Joh; Ishizuka, Takamitsu; Arisawa, Tomiyasu; Hirata, Ichiro.

In: Digestion, Vol. 83, No. 3, 01.01.2011, p. 161-166.

Research output: Contribution to journalArticle

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