Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients

Makoto Nakao, Yozo Ogura, Syousuke Satake, Izumi Ito, Akihisa Iguchi, Kenji Takagi, Toshitaka Nabeshima

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

OBJECTIVES: We investigated the clinical usefulness of soluble dietary fiber (SDF) for the treatment of diarrhea during enteral nutrition in elderly patients.METHODS: This study included 10 men and 10 women (mean age ± standard deviation: 79.3 ± 5.1 y) who had diarrhea during long-term nutrition management. When administering SDF, the initial dose was 7 g and thereafter gradually increased at 1-wk intervals. After 4 wk, the administration was discontinued for 2 wk to confirm the effects of SDF.RESULTS: After the administration of SDF, serum diamine oxidase activity significantly increased (P < 0.001): The water content of the feces decreased significantly after the administration of fiber (P < 0.01). The frequency of daily bowel movements also decreased significantly (P < 0.05). Simultaneously, the fecal features improved. Concerning intestinal flora, there were no significant changes in the total number of bacteria or the number of anaerobic bacteria. The fecal pH decreased significantly 4 wk after the administration of fiber (P < 0.05). The total level of short-chain fatty acids increased significantly 4 wk after the administration of fiber (P < 0.05). There were no significant changes in the various nutritional indices. CONCLUSIONS: The administration of SDF is useful for controlling spontaneous, favorable bowel movement by improving symptoms of small intestinal mucosal atrophy and normalizing the intestinal flora.

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalNutrition
Volume18
Issue number1
DOIs
Publication statusPublished - 05-02-2002
Externally publishedYes

Fingerprint

Dietary Fiber
Enteral Nutrition
Diarrhea
Amine Oxidase (Copper-Containing)
Therapeutics
Nutrition Assessment
Anaerobic Bacteria
Volatile Fatty Acids
Feces
Atrophy
Bacteria
Water
Serum
Gastrointestinal Microbiome

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

Nakao, Makoto ; Ogura, Yozo ; Satake, Syousuke ; Ito, Izumi ; Iguchi, Akihisa ; Takagi, Kenji ; Nabeshima, Toshitaka. / Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients. In: Nutrition. 2002 ; Vol. 18, No. 1. pp. 35-39.
@article{5b8b92cac3694adb8033c430708f0241,
title = "Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients",
abstract = "OBJECTIVES: We investigated the clinical usefulness of soluble dietary fiber (SDF) for the treatment of diarrhea during enteral nutrition in elderly patients.METHODS: This study included 10 men and 10 women (mean age ± standard deviation: 79.3 ± 5.1 y) who had diarrhea during long-term nutrition management. When administering SDF, the initial dose was 7 g and thereafter gradually increased at 1-wk intervals. After 4 wk, the administration was discontinued for 2 wk to confirm the effects of SDF.RESULTS: After the administration of SDF, serum diamine oxidase activity significantly increased (P < 0.001): The water content of the feces decreased significantly after the administration of fiber (P < 0.01). The frequency of daily bowel movements also decreased significantly (P < 0.05). Simultaneously, the fecal features improved. Concerning intestinal flora, there were no significant changes in the total number of bacteria or the number of anaerobic bacteria. The fecal pH decreased significantly 4 wk after the administration of fiber (P < 0.05). The total level of short-chain fatty acids increased significantly 4 wk after the administration of fiber (P < 0.05). There were no significant changes in the various nutritional indices. CONCLUSIONS: The administration of SDF is useful for controlling spontaneous, favorable bowel movement by improving symptoms of small intestinal mucosal atrophy and normalizing the intestinal flora.",
author = "Makoto Nakao and Yozo Ogura and Syousuke Satake and Izumi Ito and Akihisa Iguchi and Kenji Takagi and Toshitaka Nabeshima",
year = "2002",
month = "2",
day = "5",
doi = "10.1016/S0899-9007(01)00715-8",
language = "English",
volume = "18",
pages = "35--39",
journal = "Nutrition",
issn = "0899-9007",
publisher = "Elsevier Inc.",
number = "1",

}

Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients. / Nakao, Makoto; Ogura, Yozo; Satake, Syousuke; Ito, Izumi; Iguchi, Akihisa; Takagi, Kenji; Nabeshima, Toshitaka.

In: Nutrition, Vol. 18, No. 1, 05.02.2002, p. 35-39.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Usefulness of soluble dietary fiber for the treatment of diarrhea during enteral nutrition in elderly patients

AU - Nakao, Makoto

AU - Ogura, Yozo

AU - Satake, Syousuke

AU - Ito, Izumi

AU - Iguchi, Akihisa

AU - Takagi, Kenji

AU - Nabeshima, Toshitaka

PY - 2002/2/5

Y1 - 2002/2/5

N2 - OBJECTIVES: We investigated the clinical usefulness of soluble dietary fiber (SDF) for the treatment of diarrhea during enteral nutrition in elderly patients.METHODS: This study included 10 men and 10 women (mean age ± standard deviation: 79.3 ± 5.1 y) who had diarrhea during long-term nutrition management. When administering SDF, the initial dose was 7 g and thereafter gradually increased at 1-wk intervals. After 4 wk, the administration was discontinued for 2 wk to confirm the effects of SDF.RESULTS: After the administration of SDF, serum diamine oxidase activity significantly increased (P < 0.001): The water content of the feces decreased significantly after the administration of fiber (P < 0.01). The frequency of daily bowel movements also decreased significantly (P < 0.05). Simultaneously, the fecal features improved. Concerning intestinal flora, there were no significant changes in the total number of bacteria or the number of anaerobic bacteria. The fecal pH decreased significantly 4 wk after the administration of fiber (P < 0.05). The total level of short-chain fatty acids increased significantly 4 wk after the administration of fiber (P < 0.05). There were no significant changes in the various nutritional indices. CONCLUSIONS: The administration of SDF is useful for controlling spontaneous, favorable bowel movement by improving symptoms of small intestinal mucosal atrophy and normalizing the intestinal flora.

AB - OBJECTIVES: We investigated the clinical usefulness of soluble dietary fiber (SDF) for the treatment of diarrhea during enteral nutrition in elderly patients.METHODS: This study included 10 men and 10 women (mean age ± standard deviation: 79.3 ± 5.1 y) who had diarrhea during long-term nutrition management. When administering SDF, the initial dose was 7 g and thereafter gradually increased at 1-wk intervals. After 4 wk, the administration was discontinued for 2 wk to confirm the effects of SDF.RESULTS: After the administration of SDF, serum diamine oxidase activity significantly increased (P < 0.001): The water content of the feces decreased significantly after the administration of fiber (P < 0.01). The frequency of daily bowel movements also decreased significantly (P < 0.05). Simultaneously, the fecal features improved. Concerning intestinal flora, there were no significant changes in the total number of bacteria or the number of anaerobic bacteria. The fecal pH decreased significantly 4 wk after the administration of fiber (P < 0.05). The total level of short-chain fatty acids increased significantly 4 wk after the administration of fiber (P < 0.05). There were no significant changes in the various nutritional indices. CONCLUSIONS: The administration of SDF is useful for controlling spontaneous, favorable bowel movement by improving symptoms of small intestinal mucosal atrophy and normalizing the intestinal flora.

UR - http://www.scopus.com/inward/record.url?scp=0036148488&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036148488&partnerID=8YFLogxK

U2 - 10.1016/S0899-9007(01)00715-8

DO - 10.1016/S0899-9007(01)00715-8

M3 - Article

C2 - 11827762

AN - SCOPUS:0036148488

VL - 18

SP - 35

EP - 39

JO - Nutrition

JF - Nutrition

SN - 0899-9007

IS - 1

ER -