TY - JOUR
T1 - Utility and Applicability of Rapid Diagnostic Testing in Antimicrobial Stewardship in the Asia-Pacific Region
T2 - A Delphi Consensus
AU - Apisarnthanarak, Anucha
AU - Bin Kim, Hong
AU - Moore, Luke S.P.
AU - Xiao, Yonghong
AU - Singh, Sanjeev
AU - Doi, Yohei
AU - Kwa, Andrea Lay Hoon
AU - Ponnampalavanar, Sasheela Sri La Sri
AU - Cao, Qing
AU - Kim, Shin Woo
AU - Lee, Hyukmin
AU - Santanirand, Pitak
N1 - Publisher Copyright:
© 2021 The Author(s). Published by Oxford University Press for the Infectious Diseases Society of America.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - Rapid diagnostic tests (RDTs) facilitate fast and accurate identification of infectious disease microorganisms and are a valuable component of multimodal antimicrobial stewardship (AMS) programs but are currently underutilized in the Asia-Pacific region. An experienced group of infectious diseases clinicians, clinical microbiologists, and a clinical pharmacist used a modified Delphi consensus approach to construct 10 statements, aiming to optimize the utility and applicability of infection-related RDTs for AMS in the Asia-Pacific region. They provide guidance on definition, types, optimal deployment, measuring effectiveness, and overcoming key challenges. The Grading of Recommendations Assessment, Development, and Evaluation system was applied to indicate the strength of the recommendation and the quality of the underlying evidence. Given the diversity of the Asia-Pacific region, the trajectory of RDT development will vary widely; the collection of local data should be prioritized to allow realization and optimization of the full benefits of RDTs in AMS.
AB - Rapid diagnostic tests (RDTs) facilitate fast and accurate identification of infectious disease microorganisms and are a valuable component of multimodal antimicrobial stewardship (AMS) programs but are currently underutilized in the Asia-Pacific region. An experienced group of infectious diseases clinicians, clinical microbiologists, and a clinical pharmacist used a modified Delphi consensus approach to construct 10 statements, aiming to optimize the utility and applicability of infection-related RDTs for AMS in the Asia-Pacific region. They provide guidance on definition, types, optimal deployment, measuring effectiveness, and overcoming key challenges. The Grading of Recommendations Assessment, Development, and Evaluation system was applied to indicate the strength of the recommendation and the quality of the underlying evidence. Given the diversity of the Asia-Pacific region, the trajectory of RDT development will vary widely; the collection of local data should be prioritized to allow realization and optimization of the full benefits of RDTs in AMS.
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U2 - 10.1093/cid/ciab910
DO - 10.1093/cid/ciab910
M3 - Article
C2 - 34665855
AN - SCOPUS:85131903306
SN - 1058-4838
VL - 74
SP - 2067
EP - 2076
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 11
ER -