TY - JOUR
T1 - Utility of phase contrast MR imaging for assessment of pulmonary flow and pressure estimation in patients with pulmonary hypertension
T2 - Comparison with right heart catheterization and echocardiography
AU - Nogami, Munenobu
AU - Ohno, Yoshiharu
AU - Koyama, Hisanobu
AU - Kono, Atsushi
AU - Takenaka, Daisuke
AU - Kataoka, Toshiya
AU - Kawai, Hiroya
AU - Kawamitsu, Hideaki
AU - Onishi, Yumiko
AU - Matsumoto, Keiko
AU - Matsumoto, Sumiaki
AU - Sugimura, Kazuro
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2009/11
Y1 - 2009/11
N2 - Purpose: To compare the utility of phase contrast MR imaging (PC-MRI) for assessment of pulmonary flow and pressure estimation with that of right heart catheterization and echocardiography (cardiac US) in patients with pulmonary arterial hypertension (PAH). Materials and Methods: Twenty consecutive patients with suspected PAH underwent PC-MRI, cardiac US, and right heart catheterization. In each patient, PC-MRI was acquired by cine 2D-PC method on a 1.5 Tesla scanner, and stroke volume (SV) and pulmonary arterial systolic pressure (PASP) were assessed by using the modified Bernoulli's equation. To evaluate the agreements of SV and PASP among the three methods, correlations and limits of agreement among the three methods were statistically assessed by using the Bland-Altman's analyses. Results: The correlations and limits of agreement for SV and PASP between PC-MRI and catheterization (r = 0.96, r 2 = 0.94, 1.1 ± 6.9 mL and r = 0.94, r2 = 0.88, -3.2 ± 14.5 mmHg, respectively) were better than between cardiac US and catheterization (r = 0.01, r2 < 0.01, 8.9 ± 42.1 mL and r = 0.86, r2 = 0.72, -5.9 ± 27.7 mmHg, respectively). Conclusion: PC-MRI is more compatible with right heart catheterization than cardiac US in pulmonary flow and pressure estimation.
AB - Purpose: To compare the utility of phase contrast MR imaging (PC-MRI) for assessment of pulmonary flow and pressure estimation with that of right heart catheterization and echocardiography (cardiac US) in patients with pulmonary arterial hypertension (PAH). Materials and Methods: Twenty consecutive patients with suspected PAH underwent PC-MRI, cardiac US, and right heart catheterization. In each patient, PC-MRI was acquired by cine 2D-PC method on a 1.5 Tesla scanner, and stroke volume (SV) and pulmonary arterial systolic pressure (PASP) were assessed by using the modified Bernoulli's equation. To evaluate the agreements of SV and PASP among the three methods, correlations and limits of agreement among the three methods were statistically assessed by using the Bland-Altman's analyses. Results: The correlations and limits of agreement for SV and PASP between PC-MRI and catheterization (r = 0.96, r 2 = 0.94, 1.1 ± 6.9 mL and r = 0.94, r2 = 0.88, -3.2 ± 14.5 mmHg, respectively) were better than between cardiac US and catheterization (r = 0.01, r2 < 0.01, 8.9 ± 42.1 mL and r = 0.86, r2 = 0.72, -5.9 ± 27.7 mmHg, respectively). Conclusion: PC-MRI is more compatible with right heart catheterization than cardiac US in pulmonary flow and pressure estimation.
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U2 - 10.1002/jmri.21935
DO - 10.1002/jmri.21935
M3 - Article
C2 - 19856412
AN - SCOPUS:70350465303
SN - 1053-1807
VL - 30
SP - 973
EP - 980
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 5
ER -