TY - JOUR
T1 - Vitamin E and coenzyme Q concentrations in the thyroid tissues of patients with various thyroid disorders
AU - Mano, Toshiki
AU - Iwase, Katumi
AU - Hayashi, Ritsuko
AU - Hayakawa, Nobuki
AU - Uchimura, Keiko
AU - Makino, Masaki
AU - Nagata, Mutsuko
AU - Sawai, Yosikuni
AU - Oda, Naohisa
AU - Hamada, Michiko
AU - Aono, Toshihiro
AU - Nakai, Akira
AU - Nagasaka, Akio
AU - Itoh, Mitsuyasu
PY - 1998
Y1 - 1998
N2 - To clarify the different roles of free radical scavenging systems in various thyroid disorders, we measured the levels of α-, β-, and γ- tocopherols and coenzyme Q in the thyroid tissues of patients with thyroid tumors and Graves' disease using high-performance liquid chromatography. The levels of α-tocopherols and γ-tocopherols in the thyroid tissue of patients with papillary carcinoma and the level of γ-tocopherol in the thyroid tissue of patients with malignant lymphoma were elevated compared with those in normal thyroid tissues. The level of coenzyme Q was reduced in the thyroid tissue of patients with Graves' disease and follicular and papillary thyroid carcinomas. These findings imply that vitamin E and coenzyme Q as scavengers play some role in thyroid follicular cell hyperfunction or dysfunction.
AB - To clarify the different roles of free radical scavenging systems in various thyroid disorders, we measured the levels of α-, β-, and γ- tocopherols and coenzyme Q in the thyroid tissues of patients with thyroid tumors and Graves' disease using high-performance liquid chromatography. The levels of α-tocopherols and γ-tocopherols in the thyroid tissue of patients with papillary carcinoma and the level of γ-tocopherol in the thyroid tissue of patients with malignant lymphoma were elevated compared with those in normal thyroid tissues. The level of coenzyme Q was reduced in the thyroid tissue of patients with Graves' disease and follicular and papillary thyroid carcinomas. These findings imply that vitamin E and coenzyme Q as scavengers play some role in thyroid follicular cell hyperfunction or dysfunction.
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U2 - 10.1097/00000441-199804000-00002
DO - 10.1097/00000441-199804000-00002
M3 - Article
C2 - 9537635
AN - SCOPUS:0031978966
SN - 0002-9629
VL - 315
SP - 230
EP - 232
JO - American Journal of the Medical Sciences
JF - American Journal of the Medical Sciences
IS - 4
ER -