Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer

K. Takizawa, M. Maruta, K. Maeda, T. Utsumi, K. Masumori, M. Matsumoto, Y. Koide, H. Aoyama, K. Senda, O. Ishihara, H. Matsuoka

Research output: Contribution to journalArticlepeer-review

Abstract

A weekly infusion of high dose 5-fluorouracil by way of the hepatic artery has been performed in 23 cases with synchronous metastasis from colorectal cancer since 1993. The prognosis in these cases was compared with 94 cases treated without infusion chemotherapy in 94 cases before 1992. The overall one-year and three-year survival rate was 64.8% and 30.2%, respectively, in cases with infusion chemotherapy. The one-year and three-year survival rate was 42.8% and 18.6%, respectively, in cases without infusion chemotherapy. Overall survival rate was significantly different between cases with and without infusion chemotherapy (p < 0.05). In conclusion, weekly infusion chemotherapy resulted in a better survival rate than without infusion chemotherapy.

Original languageEnglish
Pages (from-to)1718-1720
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume26
Issue number12
Publication statusPublished - 10-1999

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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