Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer

K. Takizawa; M. Maruta; Koutaro Maeda; Toshiaki Utsumi; K. Masumori; M. Matsumoto; Y. Koide; H. Aoyama; K. Senda; O. Ishihara; H. Matsuoka

Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer

K. Takizawa
, M. Maruta
, Koutaro Maeda
, Toshiaki Utsumi
, K. Masumori
, M. Matsumoto
, Y. Koide
, H. Aoyama
, K. Senda
, O. Ishihara
, H. Matsuoka

Research output: Contribution to journal › Article › peer-review

Abstract

A weekly infusion of high dose 5-fluorouracil by way of the hepatic artery has been performed in 23 cases with synchronous metastasis from colorectal cancer since 1993. The prognosis in these cases was compared with 94 cases treated without infusion chemotherapy in 94 cases before 1992. The overall one-year and three-year survival rate was 64.8% and 30.2%, respectively, in cases with infusion chemotherapy. The one-year and three-year survival rate was 42.8% and 18.6%, respectively, in cases without infusion chemotherapy. Overall survival rate was significantly different between cases with and without infusion chemotherapy (p < 0.05). In conclusion, weekly infusion chemotherapy resulted in a better survival rate than without infusion chemotherapy.

Original language	English
Pages (from-to)	1718-1720
Number of pages	3
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	26
Issue number	12
Publication status	Published - 10-1999

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

Cite this

@article{6f74f0c2a1a5467995a2aa9c5f9711f6,

title = "Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer",

abstract = "A weekly infusion of high dose 5-fluorouracil by way of the hepatic artery has been performed in 23 cases with synchronous metastasis from colorectal cancer since 1993. The prognosis in these cases was compared with 94 cases treated without infusion chemotherapy in 94 cases before 1992. The overall one-year and three-year survival rate was 64.8\% and 30.2\%, respectively, in cases with infusion chemotherapy. The one-year and three-year survival rate was 42.8\% and 18.6\%, respectively, in cases without infusion chemotherapy. Overall survival rate was significantly different between cases with and without infusion chemotherapy (p < 0.05). In conclusion, weekly infusion chemotherapy resulted in a better survival rate than without infusion chemotherapy.",

author = "K. Takizawa and M. Maruta and Koutaro Maeda and Toshiaki Utsumi and K. Masumori and M. Matsumoto and Y. Koide and H. Aoyama and K. Senda and O. Ishihara and H. Matsuoka",

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year = "1999",

month = oct,

language = "English",

volume = "26",

pages = "1718--1720",

journal = "Gan to kagaku ryoho. Cancer \& chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

number = "12",

}

TY - JOUR

T1 - Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer

AU - Takizawa, K.

AU - Maruta, M.

AU - Maeda, Koutaro

AU - Utsumi, Toshiaki

AU - Masumori, K.

AU - Matsumoto, M.

AU - Koide, Y.

AU - Aoyama, H.

AU - Senda, K.

AU - Ishihara, O.

AU - Matsuoka, H.

N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

PY - 1999/10

Y1 - 1999/10

N2 - A weekly infusion of high dose 5-fluorouracil by way of the hepatic artery has been performed in 23 cases with synchronous metastasis from colorectal cancer since 1993. The prognosis in these cases was compared with 94 cases treated without infusion chemotherapy in 94 cases before 1992. The overall one-year and three-year survival rate was 64.8% and 30.2%, respectively, in cases with infusion chemotherapy. The one-year and three-year survival rate was 42.8% and 18.6%, respectively, in cases without infusion chemotherapy. Overall survival rate was significantly different between cases with and without infusion chemotherapy (p < 0.05). In conclusion, weekly infusion chemotherapy resulted in a better survival rate than without infusion chemotherapy.

AB - A weekly infusion of high dose 5-fluorouracil by way of the hepatic artery has been performed in 23 cases with synchronous metastasis from colorectal cancer since 1993. The prognosis in these cases was compared with 94 cases treated without infusion chemotherapy in 94 cases before 1992. The overall one-year and three-year survival rate was 64.8% and 30.2%, respectively, in cases with infusion chemotherapy. The one-year and three-year survival rate was 42.8% and 18.6%, respectively, in cases without infusion chemotherapy. Overall survival rate was significantly different between cases with and without infusion chemotherapy (p < 0.05). In conclusion, weekly infusion chemotherapy resulted in a better survival rate than without infusion chemotherapy.

UR - https://www.scopus.com/pages/publications/0033210161

UR - https://www.scopus.com/pages/publications/0033210161#tab=citedBy

M3 - Article

C2 - 10560379

AN - SCOPUS:0033210161

SN - 0385-0684

VL - 26

SP - 1718

EP - 1720

JO - Gan to kagaku ryoho. Cancer & chemotherapy

JF - Gan to kagaku ryoho. Cancer & chemotherapy

IS - 12

ER -

Weekly hepatic arterial infusion of high dose 5-fluorouracil for liver metastasis from colorectal cancer

Abstract

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All Science Journal Classification (ASJC) codes

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