TY - JOUR
T1 - Whole-body MR imaging vs. FDG-PET
T2 - Comparison of accuracy of M-stage diagnosis for lung cancer patients
AU - Ohno, Yoshiharu
AU - Koyama, Hisanobu
AU - Nogami, Munenobu
AU - Takenaka, Daisuke
AU - Yoshikawa, Takeshi
AU - Yoshimura, Masahiro
AU - Kotani, Yoshikazu
AU - Nishimura, Yoshihiro
AU - Higashino, Takanori
AU - Sugimura, Kazuro
PY - 2007/9
Y1 - 2007/9
N2 - Purpose: To conduct a prospective comparison of the accuracy of whole-body MR imaging and positron emission tomography (PET) with fluorine-18 deoxyglucose (FDG) (FDG-PET) to assess the M-stage in lung cancer patients. Materials and Methods: A total of 90 consecutive lung cancer patients (mean age = 68 years) underwent whole-body MR imaging and FDG-PET as well as other standard radiological imaging procedures before and after treatment. Probabilities of metastases on whole-body MR imaging and FDG-PET were assessed by using 5-point scoring systems on a per-site basis and on a per-patient basis. Receiver operating characteristic (ROC) curve analysis was used to compare diagnostic capabilities. Sensitivity, specificity, and accuracy were also compared by using the McNemar's test on a per-site and per-patient basis. Results: For assessment of head and neck metastases and bone metastases, accuracies of whole-body MR imaging (95.0% and 94.8%, respectively) were significantly higher than those of FDG-PET (89.1% and 88.2%, respectively; P < 0.05). For assessment of the M-stage on a per-patient basis, accuracy of whole-body MR imaging (80.0%) was also significantly higher than that of FDG-PET (73.3%; P < 0.05). Conclusion: Whole-body MR imaging is an accurate diagnostic technique and may be considered at least as effective as FDG-PET for assessment of the M-stage of lung cancer patients.
AB - Purpose: To conduct a prospective comparison of the accuracy of whole-body MR imaging and positron emission tomography (PET) with fluorine-18 deoxyglucose (FDG) (FDG-PET) to assess the M-stage in lung cancer patients. Materials and Methods: A total of 90 consecutive lung cancer patients (mean age = 68 years) underwent whole-body MR imaging and FDG-PET as well as other standard radiological imaging procedures before and after treatment. Probabilities of metastases on whole-body MR imaging and FDG-PET were assessed by using 5-point scoring systems on a per-site basis and on a per-patient basis. Receiver operating characteristic (ROC) curve analysis was used to compare diagnostic capabilities. Sensitivity, specificity, and accuracy were also compared by using the McNemar's test on a per-site and per-patient basis. Results: For assessment of head and neck metastases and bone metastases, accuracies of whole-body MR imaging (95.0% and 94.8%, respectively) were significantly higher than those of FDG-PET (89.1% and 88.2%, respectively; P < 0.05). For assessment of the M-stage on a per-patient basis, accuracy of whole-body MR imaging (80.0%) was also significantly higher than that of FDG-PET (73.3%; P < 0.05). Conclusion: Whole-body MR imaging is an accurate diagnostic technique and may be considered at least as effective as FDG-PET for assessment of the M-stage of lung cancer patients.
UR - http://www.scopus.com/inward/record.url?scp=35248821350&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35248821350&partnerID=8YFLogxK
U2 - 10.1002/jmri.21031
DO - 10.1002/jmri.21031
M3 - Review article
C2 - 17729341
AN - SCOPUS:35248821350
VL - 26
SP - 498
EP - 509
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
SN - 1053-1807
IS - 3
ER -